IRCT2012072410379N1 IRCT 2013-08-21 Vice Chancellor for Research, Birjand University of Medical Sciences Effect of vitamin C and E supplements on mother's milk Clinical trial of comparison of vitamin C and E supplements effect on total antioxidant capacity of healthy women's breast milk in experimental and control groups 2009-03-21 anticipated 60 Complete https://irct.ir/trial/10889 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: In this study, mothers were the criterion for randomization, and infants were placed in the similar group of their mothers after randomizing the mothers. The first mother and her infant were randomly placed in one of the two groups, either the experimental group or the control group, by selecting a card from two cards on which were written the terms "control" and "experimental". The other mothers together with their infants were assigned to the two groups alternately. Mothers in the experimental group were given 30 effervescent tablets of vitamin C and 30 chewable tablets of vitamin E. They should take one tablet from each two kinds of supplements on a daily basis. The control group did not receive any intervention. It is noteworthy that the mothers in the experimental and control groups were on free diet. The measurement of the antioxidant indices in infants’ urine was only done with the aim of a better evaluation of the intervention effect on the antioxidant capacity of mothers’ milk. N/A Effect of supplements on total antioxidant capacity of human breast milk. Mothers in the experimental group: 30 effervescent tablets of vitamin C (500 mg) and 30 chewable tablets of vitamin E (100 IU is equal to 100 mg) were given to them, and they should take one tablet from each two kinds of supplements on a daily basis. Mothers in the control group: They received no intervention and were on free diet..