IRCT2016031627072N1 IRCT 2016-05-19 Vice chancellor for research, Shahid Beheshti University Skin Research Center of Medical Science The combination of NBUVB, co2 fractional laser treatment of vitiligo Evaluation of combination treatment by co 2 fractional laser on the margin of lesions and Narrow Band Ultraviolet Band in vitiligo patients referred to Shohada-e- Tajrish and Loghman-e - Hakim hospitals during years 1394- 1396 2016-01-28 anticipated 30 Complete https://irct.ir/trial/22273 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 2-3 VITILIGO. Intervention 1: Case: The treatment method is, Korean MIXEL, DIOD Laser with 10 to 20 m j energy was used in the 1 cm margin of each lesion in one side. One week after laser, the Patient will exposed to NBUVB in standard Walkman's cabin with 3 times weekly. Primary energy was 0/1 to 0/2 j/ cm 2, and according to patient's skin tolerance and Treatment response it will be increased to 2 j/cm 2 gradually and will continues for 6 months. Intervention 2: Control: to NBUVB in standard Walkman's cabin with 3 times weekly. Primary energy was 0/1 to 0/2 j/ cm 2, and according to patient's skin tolerance and Treatment response it will be increased to 2 j/cm 2 gradually and will continues for 6 months.