]>
IRCT20180222038827N1 IRCT 2018-03-10 Tehran University of Medical Sciences Evaluation of Effect of Light Emitting Diode ( LED) on the َAllograft Bone after the Open Sinus Lift ( A Randomized clinical trial study) Evaluation of Effect of Light Emitting Diode ( LED) on the َAllograft Bone after the Open Sinus Lift ( A Randomized clinical trial study) 2017-02-19 anticipated 40 Complete https://irct.ir/trial/29772 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Other design features: none, Randomization description: Patients were randomly assigned to a number ranging from 1 to 40. The number of individuals in the case and paired numbers were in the control group, each group containing 20 patients, Blinding description: In this study, the pathologist examines the histology of the specimens and the surgeries that have undergone the surgical procedure and the sampling have been kept blind. N/A edentoulism. Intervention 1: Intervention group: Sinus Lifting and LED. Intervention 2: Control group: Sinus lifting. Yes - There is a plan to make this available What will be shared: All data has subscription capability. When: starting 6 months after publication To whom: all peaple Conditions: none Where to obtain: email to dr. Arshad How to obtain: none Comments:
public Mahnaz Arshad
Unit 9, 3th Floor, Number 3, first Alley, Sanjabi Street, Madar Square, Mirdamad Street, Tehran, Iran
Tehran Iran (Islamic Republic of) 19119-33963 +98 21 2227 3471 Arshad-m@tums.ac.ir Tehran University of Medical Sciences scientific Mahnaz Arshad
Unit 9, 3th Floor, Number 3, first Alley, Sanjabi Street, Madar Square, Mirdamad Street, Tehran, Iran
Tehran Iran (Islamic Republic of) 19119-33963 +98 21 2227 3471 mahnazarshad@yahoo.com Tehran University of Medical Sciences Iran (Islamic Republic of) Have no chronic sinus disease There is no chronic bone marrow disease There is no history of surgery in the area Do not have diabetes Knowingly sign the consent form of the company in the research. Have no history of radiotherapy and chemotherapy Maxillary premolars edentoulism 20 years 80 years Both Smoking Chronic sinus disease Diabets History of cancer Consumption ofBisphosphonates Failure to use LED device Treatment - Devices Treatment - Surgery Intervention group: Sinus Lifting and LED Control group: Sinus lifting Maxillary premolar missing. Timepoint: Group A received LED phototherapy (Biolux Ltd, Vancover, Canada) with continuous wave length of 620 nm, 20 min/day for 21 days, after sinus lifting procedure. After 6 months, the sinus graft sites were re-opened to insertion of dental implants and bony biopsies were taken simultaneously. Method of measurement: A blind examiner (maxillofacial pathologist) analyzed each sample with a light microscope. In histological evaluations of these cases, following items were examined and graded as mentioned below:Degree of inflammation: defined as the following numbers: 1 = absence of inflammation, 2 = moderate inflammation and 3 = severe inflammation. Formation and bone quality: defined as the following numbers: 1 = connective tissue containing blood vessels, fibroblasts, macrophages, collagen fibers, 2 = dense connective tissue with the presence of large number of cells that differentiate into bone tissue which represents the initiation of bone formation, 3 = formation of new bone tissue, dense connective tissue, 4 = obvious bony tissues. The density of collagen fibers (maturation): it defined as the following numbers: 1 = absence of collagen fibers, 2 = average density of collagen fibers, 3 = high density of collagen fibers without a regular structure (assessed by using polarized light), 4 = extreme density of collagen fibers with a definite structure (assessed by using polarized light) based on a pathologist's judgment after viewing all the samples at ×100 magnification. Tehran University of Medical Sciences Approved 2018-02-24 Ethics Committee of Tehran University of Medical Sciences Unit 9, 3th Floor, Number 3, first Alley, Sanjabi Street, Madar Square, Mirdamad Street, Tehran, Iran Tehran Tehran Iran (Islamic Republic of)