IRCT20121001010980N4 IRCT 2020-05-28 Endocrinology and Metabolism Research Institute Evaluation of Levothyroxin therapy on Oxidant and anti Oxidant level in subclinical hypothyroid patients comparison of oxidant and anti oxidant level after levothyroxin therapy between subclinical hypothyroid patients and normal group 2016-04-04 anticipated 30 Complete https://irct.ir/trial/29873 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Basic scienece, Randomization description: The randomization method is block randomization. The unit of randomization is the individual. The randomization tool is statistical software and the method of making random sequences obtained by the software is done According to the table, coded envelopes with a random sequence were used to allocation concealment, Blinding description: Participants, principal investigators, data collection authorities, and those who assess the outcome and patients (after obtaining written consent) are blinded to which patient was in the drug group and which patient was in the placebo group. The blinding was done using small envelopes containing medicine or placebo on which the code A or B was written based on a random table. 3 subclinical hypothyroidism. Intervention 1: Intervention group: Levothyroxine tablet treatment intervention group with 50 micrograms once daily orally for 3 months (Iran Hormone Company 2). Intervention 2: Control group: In this group placebo , made by the Faculty of Pharmacy of Tehran University of Medical Sciences, were given orally administered once a day for 3 months. Yes - There is a plan to make this available What will be shared: main outcome data When: 6 months after publication To whom: Researchers working in scientific institutes Conditions: Use study variables for other research in this area Where to obtain: Nooshin Shirzad nshirzad11@gmail.com How to obtain: Request through the Scientific Institute Comments: