]>
IRCT20180813040779N1 IRCT 2018-08-26 Yazd University of Medical Sciences Effect of pleurodesis and bleomycin in malignant pleural effusions Evaluation of success rate of pleurodesis with negative pressure suction and bleomycin in malignant pleural effusions 2018-09-23 anticipated 25 Complete https://irct.ir/trial/33304 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 3 Pleural effusion. Intervention group: In patients with malignant pleural effusion, 15 ml of lidocaine 2% is injected into the chest tube, and bleomycin 1 mg/kg is injected into the chest tube with 50 ml normal saline to be diluted. Then the clamp is released and an hour later, the clamp is opened and lung fluid is pulled out using 20cmH2O negative pressure.. Yes - There is a plan to make this available What will be shared: I will decide after collecting of all data When: Six months after publishing the results. To whom: All researchers Conditions: With email request Where to obtain: Masoud Rahimian How to obtain: Just email Comments:
public Masoud Rahimian
Yazd University of Medical Sciences
Yazd Iran (Islamic Republic of) 8944163114 +98 35 3822 4000 m.rahimian@ssu.ac.ir Yazd University of Medical Sciences scientific Masoud Rahimian
Yazd University of Medical Sciences
Yazd Iran (Islamic Republic of) 8944163114 +98 35 3822 4000 m.rahimian@ssu.ac.ir Yazd University of Medical Sciences Iran (Islamic Republic of) Cytologically confirmed malignant pleural fluid No sensitivity to bleomycin No history of previous chemotherapy with bleomycin 18 years 80 years Both Previous history of pleurodesis History of coagulation disorders Patient dissatisfaction J90 Pleural effusion, not elsewhere classified Treatment - Drugs Intervention group: In patients with malignant pleural effusion, 15 ml of lidocaine 2% is injected into the chest tube, and bleomycin 1 mg/kg is injected into the chest tube with 50 ml normal saline to be diluted. Then the clamp is released and an hour later, the clamp is opened and lung fluid is pulled out using 20cmH2O negative pressure. The amount of pleural effusion. Timepoint: Before the intervention and four weeks after the intervention. Method of measurement: Observation. Yazd University of Medical Sciences Approved 2017-07-02 Ethics committee of Yazd University of Medical Sciences Shahid Sadughi hospital, Ghandi Blvd, Yazd Yazd Yazd Iran (Islamic Republic of)