IRCT20170614034526N2 IRCT 2018-09-26 Children Hospital and institute of Child Health Comparison of clinical efficacy and safety of injectable Levetiracetam versus Phenytoin Comparison of clinical efficacy and safety of injectable Levetiracetam versus Phenytoin as second line drug in the management of generalized convulsive status epilepticus in children: An open label randomized control trial 2014-01-27 anticipated 650 Complete https://irct.ir/trial/33671 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Children were divided into two groups by random allocation for the selection of second-line drug. Children received Levetiracetam were assigned as group A (LEV group) and those received phenytoins were assigned as group B (PHT group). Sealed envelope system was used for randomization. A set of envelopes were prepared, each bearing the name of the drug (Phenytoin and Levetiracetam were written on 300 envelopes each) on it. All envelops were sealed properly and shuffled by a person not involved in the study. These pre-written, drug named sealed envelopes were opened at the time of administration of the second-line drug for the management of CSE. 4 Generalized convulsive status epileptics.. Intervention 1: Intervention group: Group A: Levetiracetam 40mg/kg infused in 15 minutes. Intervention 2: Control group: Group B: Phenytoin 20 mg/kg infused in 30minutes. No - There is not a plan to make this available Justification or reason for not sharing IPD is To keep the confidentiality of the study participants, however, data would be made available to the Ethics Committee of the institute upon requirement