<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20180822040849N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2018-09-18</date_registration>
      <primary_sponsor>Islamic Azad University</primary_sponsor>
      <public_title>swimming HIIT training and serum levels of irisin</public_title>
      <acronym></acronym>
      <scientific_title>effect of 8 weeks of swimming HIIT training on serum levels of irisin and metabolic indicators in 50-60 years old overweight and obese women.</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2018-10-23</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>30</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/33787</url>
      <study_type>observational</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Basic scienece, Randomization description: Simple randomization: First each subject will be taken in each groups (A or B) by tossing a coin. For example the side of the coin determines the assignment of each subject. Then each group will be named as control or experiment group by tossing a coin.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Over Weight and Obesity.</hc_freetext>
      <i_freetext>Intervention 1: 30 overweight and obese women (60-50 years) will be selected as the statistical sample and randomly assigned to two experimental and control groups.  Experimental group will practice high intensity interval swimming trainings for 8 weeks, each week with 3 sessions, each session including 10 minutes of warm-up, 6-8 repetitions of 30 seconds of front crawl with maximum  speed and 2 minutes of active rest between repetitions and at the end of training, 10 minutes of cool-down trainings. During the study period, the control group will not participate in any physical activity. Before training program, and 48 hours after the last training session, measurements of waist circumference and blood pressure, as well as blood samples in the fasting state will performed  to measure irisin, glucose and insulin resistance. Intervention 2: Control group: without any exercise.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
all data

When:
6 months after publication

To whom:
academic staff

Conditions:
nothing

Where to obtain:
scientific papers

How to obtain:
searching on scientific websites

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Akram Jafari</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Rahmatieh, Islamic Azad University</address>
        <city>Shahrekord</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>8813733441</zip>
        <telephone>+98 38 3336 1000</telephone>
        <email>jafari.akm@gmail.com</email>
        <affiliation>Islamic Azad University</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Akram Jafari</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Rahmatieh, Islamic Azad Universityر</address>
        <city>Shahrekord</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>8813733441</zip>
        <telephone>+98 38332326462</telephone>
        <email>jafari.akm@gmail.com</email>
        <affiliation>Islamic Azad University</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>overweight and obese women
60-50 years
no disease
postmenopausal</inclusion_criteria>
      <agemin>50 years</agemin>
      <agemax>60 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>having disease
BMI less than 30
age less than 50</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>Z68.53</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Body mass index (BMI) pediatric, 85th percentile to less than 95th percentile for age</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>N/A</i_code>
      <i_code>N/A</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>30 overweight and obese women (60-50 years) will be selected as the statistical sample and randomly assigned to two experimental and control groups.  Experimental group will practice high intensity interval swimming trainings for 8 weeks, each week with 3 sessions, each session including 10 minutes of warm-up, 6-8 repetitions of 30 seconds of front crawl with maximum  speed and 2 minutes of active rest between repetitions and at the end of training, 10 minutes of cool-down trainings. During the study period, the control group will not participate in any physical activity. Before training program, and 48 hours after the last training session, measurements of waist circumference and blood pressure, as well as blood samples in the fasting state will performed  to measure irisin, glucose and insulin resistance</i_keyword>
      <i_keyword>Control group: without any exercise</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Irisin. Timepoint: before and after 8 weeks swimming HIIT training. Method of measurement: blood sampling.</prim_outcome>
      <prim_outcome>Glucose. Timepoint: before and after 8 weeks swimming HIIT training. Method of measurement: blood sampling.</prim_outcome>
      <prim_outcome>Insulin resistance. Timepoint: before and after 8 weeks swimming HIIT training. Method of measurement: blood sampling.</prim_outcome>
      <prim_outcome>TG. Timepoint: before and after 8 weeks swimming HIIT training. Method of measurement: blood sampling.</prim_outcome>
      <prim_outcome>HDL. Timepoint: before and after 8 weeks swimming HIIT training. Method of measurement: blood sampling.</prim_outcome>
      <prim_outcome>Blood pressure. Timepoint: before and after 8 weeks swimming HIIT training. Method of measurement: barometer.</prim_outcome>
      <prim_outcome>Waist circumference. Timepoint: before and after 8 weeks swimming HIIT training. Method of measurement: narrowest waist circumference.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Islamic Azad University</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2018-05-21</approval_date>
        <contact_name>Islamic Azad Univercity Shahrekord Branch</contact_name>
        <contact_address>Rahmatieh, Islamic Azad University Shahrekord Chahar-Mahal-va-Bakhtiari Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
