<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20140705018362N4</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2018-11-09</date_registration>
      <primary_sponsor>Ahvaz University of Medical Sciences</primary_sponsor>
      <public_title>Effects of Muscle  strengthening on Motion Characteristics in Patellofemoral Pain</public_title>
      <acronym></acronym>
      <scientific_title>Comparison of the Effectiveness of Knee and Hip_ Knee muscle Strengthening Exercises on Single Leg Squat and Step Decent  Kinematics in Individuals with Patellofemoral Pain</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2018-07-23</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>70</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/34818</url>
      <study_type>observational</study_type>
      <study_design>Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Balanced- Randomization technique will be used to allocate patients to the intervention groups. A person who has no role in the study will allocate the participants to the treatment groups. The Taves technique will be used to balance the groups with respect to demographic variables, Blinding description: The assessor and data analyst will be blinded to group allocation of the participants.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Patellofemoral Pain.</hc_freetext>
      <i_freetext>Intervention 1: Group 1: Individuals in this group will perform the hip abductor and external rotator muscle strengthening exercises in addition to knee muscles strengthening and stretching. Each individual will receive 12 sessions of treatment with the frequency of 3 sessions per week for 45 minutes in each session.  Each week, the amount of resistive load will be adjusted to 70% of the 1-repetition maximum. For exercise with the elastic band, the resistance will be adjusted to the maximum resistance each individual can use to complete 10 repetitions of the exercise with no pain.  ُtretching for the muscles interest consists of three trials of a 30-second stretch,  assisted by the therapist. Intervention 2: Treatment for group 1 includes the knee muscles strengthening and stretching exercises. Each individual will receive 12 sessions of treatment with the frequency of 3 sessions per week for 45 minutes in each session.  Each week, the amount of resistive load will be adjusted to 70% of the 1-repetition maximum. For exercise with the elastic band, the resistance will be adjusted to the maximum resistance each individual can use to complete 10 repetitions of the exercise with no pain.  ُtretching for the muscles interest consists of three trials of a 30-second stretch,  assisted by the therapist.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is There is no more information.</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Mahsa Keshavarz</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>School of Rehabilitation Sciences, University Compus, Golestan</address>
        <city>Ahvaz</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>61357-15794</zip>
        <telephone>+98 61 3374 3101</telephone>
        <email>mahsa.pt91@gmail.com</email>
        <affiliation>Ahvaz University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Fateme Esfandiarpour</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Ahvaz Jundishapour University of Medical Sciences,Ahvaz. Iran</address>
        <city>Ahvaz</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>61357-15794</zip>
        <telephone>+98 61 3374 3101</telephone>
        <email>fateme@ualberta.ca</email>
        <affiliation>Ahvaz University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Females with PFP in the age range of 18-45
Reporting Anterior Knee Pain
a minimum pain intensity of 30 based on a 100-mm visual analogue scale
َA history of Knee Pain in the last 2 months
Anterior Knee pain in at least 2 daily activities of  ascending and descending stairs, squatting, kneeling, long sitting
pain on palpation of the medial and/or lateral facet of patella</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>45 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>Ligament instability
Signs or symptoms of meniscal injury or any intra-articular disorder
more than trace knee effusion
Neural system involvmen that leading to walking disorer
Osgood's_ Schlatter syndrome
positive Apprehension Test
excessive  foot pronation, excessive knee valgus/varus
Hip pain, sacroiliac pain, back pain
patella, iliotibial band and pes anserinus tendonitist
A history of Patellar dislocation</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M22.4</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Chondromalacia patellae</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Group 1: Individuals in this group will perform the hip abductor and external rotator muscle strengthening exercises in addition to knee muscles strengthening and stretching. Each individual will receive 12 sessions of treatment with the frequency of 3 sessions per week for 45 minutes in each session.  Each week, the amount of resistive load will be adjusted to 70% of the 1-repetition maximum. For exercise with the elastic band, the resistance will be adjusted to the maximum resistance each individual can use to complete 10 repetitions of the exercise with no pain.  ُtretching for the muscles interest consists of three trials of a 30-second stretch,  assisted by the therapist.</i_keyword>
      <i_keyword>Treatment for group 1 includes the knee muscles strengthening and stretching exercises. Each individual will receive 12 sessions of treatment with the frequency of 3 sessions per week for 45 minutes in each session.  Each week, the amount of resistive load will be adjusted to 70% of the 1-repetition maximum. For exercise with the elastic band, the resistance will be adjusted to the maximum resistance each individual can use to complete 10 repetitions of the exercise with no pain.  ُtretching for the muscles interest consists of three trials of a 30-second stretch,  assisted by the therapist.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Maximal Isometric strength of Quadriceps muscles. Timepoint: Before and after treatment. Method of measurement: A fixed dynamometer.</prim_outcome>
      <prim_outcome>Maximal Isometric strength of  hamstring muscles. Timepoint: Before and after treatment. Method of measurement: a fixed dynamometer.</prim_outcome>
      <prim_outcome>Maximal isometric strength of Hip external rotators and Abductor Muscles. Timepoint: Before and after treatment. Method of measurement: a fixed dynamometer.</prim_outcome>
      <prim_outcome>Knee flexion angle. Timepoint: Before and after treatment. Method of measurement: Motion Analysis System.</prim_outcome>
      <prim_outcome>Hip flexion angle. Timepoint: before and after treatment. Method of measurement: Motion Analysis system.</prim_outcome>
      <prim_outcome>Hip internal/external rotation angle. Timepoint: before and after treatment. Method of measurement: Motion analysis system.</prim_outcome>
      <prim_outcome>Hip Abduction/adduction angle. Timepoint: before and after treatment. Method of measurement: Motion analysis system.</prim_outcome>
      <prim_outcome>Knee abduction/adduction angle. Timepoint: before and after treatment. Method of measurement: Motion analysis system.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Pain  intensity. Timepoint: Before and after treatment. Method of measurement: Visual Analog scale.</sec_outcome>
      <sec_outcome>Function. Timepoint: Before and after treatment. Method of measurement: Kujala Questionnaire and the step-down test.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Ahvaz University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2018-06-09</approval_date>
        <contact_name>The Ethics Committee of Ahvaz Jundishapur University of Medical Sciences</contact_name>
        <contact_address>Central Office, University Campus, Golestan Ahvaz Khouzestan Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
