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IRCT20140503017537N6 IRCT 2019-02-03 Kermanshah University of Medical Sciences The effects of hydrogen peroxide irrigation on postoperative complications of rhinoplasty Comparison of the effects of hydrogen peroxide and normal saline irrigation on postoperative complications of rhinoplasty in patients undergoing rhinoplasty 2019-03-05 anticipated 44 Complete https://irct.ir/trial/36483 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Randomization description: A random number generation technique will be used in the Excel environment, so that a code is assigned to each patient before starting the study using the random numbers table. Depending on the last digit of the assigned code, the type of treatment being selected. If the last digit of the code is even ( 0, 2, 4, 6, 8) the patient is placed in the hydrogen peroxide group, and if it is odd, the patient is placed in the control group. By this method, allocation of each patient to the hydrogen peroxide group or normal saline group is accomplished by simple randomization technique, Blinding description: A secretary who has no role in the study assigns a code to each patient using the random code table. These codes that identify the patient group are sealed and closed until the completion of the study in an envelope. Therefore, random allocation and allocation concealment is achieved for both the patients as well as the operators, examiners, surgeons and clinicians. 3 postoperative complications of rhinoplasty. Intervention 1: Intervention group: After the operation has finished, before dressing the wound , the surgical field is washed with hydrogen peroxide (3%) (which is made immediately before the process and kept in good condition away from light). Intervention 2: Control group: After the operation has finished, before dressing the wound , the surgical field is washed with normal saline. No - There is not a plan to make this available Justification or reason for not sharing IPD is There are no further information available
public Hesamedin Nazari
School of Dentistry, Shariati St.
Kermanshah Iran (Islamic Republic of) 6713954658 +98 918 856 5291 h.nazari@kums.ac.ir Kermanshah University of Medical Sciences scientific Hesamedin Nazari
School of Dentistry, Shariati St.
Kermanshah Iran (Islamic Republic of) 6713954658 +98 918 856 5291 h.nazari@kums.ac.ir Kermanshah University of Medical Sciences Iran (Islamic Republic of) Patients undergoing rhinoplasty right after the operation no limit no limit Both Opioid, drug and alcohol abusers History of previous or present systemic diseases and continuous use of drugs daily use of analgesics or using them 24 hours before the operation Patients who can not cooperate Treatment - Drugs Placebo Intervention group: After the operation has finished, before dressing the wound , the surgical field is washed with hydrogen peroxide (3%) (which is made immediately before the process and kept in good condition away from light). Control group: After the operation has finished, before dressing the wound , the surgical field is washed with normal saline. Severity of postoperative pain. Timepoint: At intervals 2, 6, 12 to 24 hours after surgery. Method of measurement: using the Visual Analogue Scale(VAS). Severity of postoperative swelling. Timepoint: At intervals of 1 week, 2 weeks, 4 weeks and 8 weeks after surgery. Method of measurement: using the Surgeon Periorbital Rating of Edema and Ecchymosis (SPREE). Severity of postoperative edema. Timepoint: On days 1,2,5,7,10 after surgery. Method of measurement: using the Surgeon Periorbital Rating of Edema and Ecchymosis (SPREE). Severity of postoperative echymosis. Timepoint: On days 1,2,5,7,10 after surgery. Method of measurement: using the Surgeon Periorbital Rating of Edema and Ecchymosis (SPREE). Amount of postoperative bleeding. Timepoint: On the first day after surgery. Method of measurement: Counting the number of dressing needed. Severity of postoperative inflammation. Timepoint: During the first week after surgery. Method of measurement: using the +-. Severity of postoperative infection. Timepoint: During the first week after surgery. Method of measurement: using the +-. Kermanshah University of Medical Sciences Approved 2018-12-26 Committee of Ethics in Research - Kermanshah University of Medical Sciences Committee of Ethics in Research, Vice chancellor for research and technology, Kermanshah University of Medical Sciences, Shahid Beheshti Blvd. Kermanshah Kermanshah Iran (Islamic Republic of)