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IRCT20190326043113N1 IRCT 2019-05-09 Mazandaran University of Medical Sciences Comparative study of nano-emulsion fluconazole gel with oral form in dermatophyte treatment Comparative study of the efficacy of topical nano-emulsion fluconazole gel with its oral drug form in the treatment of dermatophytosis infections 2018-09-23 anticipated 40 Complete https://irct.ir/trial/38619 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: we gave the doctor a specific number of two groups of medicine and a placebo, and the doctor treated the patient by random, Blinding description: As a researcher, I divided the medication and placebo into 2 groups A and B and gave the physician the right to distribute the drug among the patients without knowing which group contains topical treatment and which group contains oral treatment. 2-3 Cutaneous dermatophyte. Intervention 1: Intervention group: receivers of the topical Fluconazole Nano-emolgel, formulated in the Pharmaceutical Laboratory of the Faculty of Pharmacy, and an oral placebo containing filled with avicel capsules.Patients receive medication for four weeks and follow up every two weeks. After discontinuation of the drug, after four weeks of recurrence of disease is examined. The topical product is given twice daily and oral capsule is given weekly. Intervention 2: Control group: receivers of the topical placebo, and an oral fluconazole 150 miligram capsules.Patients receive medication for four weeks and follow up every two weeks. After discontinuation of the drug, after four weeks of recurrence of disease is examined. The topical product is given twice daily and oral capsule is given weekly. Yes - There is a plan to make this available What will be shared: Outcome of main information When: From 1398 To whom: All the researchers in this field Conditions: No further analysis is allowed on the data Where to obtain: corresponding author How to obtain: Send a requested email to the corresponding author Comments:
public ّFarnaz Rajabali
15th number, 13th block, qaderi alley, Sharifi square, Pasdaran,
Sari Iran (Islamic Republic of) 624304840015 +98 212670655 rajabali.farnaz@yahoo.com Mazandaran University of Medical Sciences scientific Farnaz Rajabali
Number 15, block 13, Qaderi alley, Sharifi square, Pasdaran
Tehran Iran (Islamic Republic of) 624304840015 +98 92126750655 rajabali.farnaz@yahoo.com Mazandaran University of Medical Sciences Iran (Islamic Republic of) Patients over 10 years old Patients with localized cutaneous dermatophytosis with a maximum of 3 to 4 patches Not taking topical or oral antifungal medicines from 4 weeks ago Not taking oral or topical steroids from 4 weeks ago 10 years no limit Both Pregnant and breastfeeding women Diabetic patients taking sulfonylureas, tolbutamide and glyburide Taking phenytoin and Coumarin Anticoagulants onichomycosis Dermatophytosis of head and beard severe Cutaneous dermatophytosis B35.4 Tinea corporis Treatment - Drugs Treatment - Drugs Intervention group: receivers of the topical Fluconazole Nano-emolgel, formulated in the Pharmaceutical Laboratory of the Faculty of Pharmacy, and an oral placebo containing filled with avicel capsules.Patients receive medication for four weeks and follow up every two weeks. After discontinuation of the drug, after four weeks of recurrence of disease is examined. The topical product is given twice daily and oral capsule is given weekly. Control group: receivers of the topical placebo, and an oral fluconazole 150 miligram capsules.Patients receive medication for four weeks and follow up every two weeks. After discontinuation of the drug, after four weeks of recurrence of disease is examined. The topical product is given twice daily and oral capsule is given weekly Scratch rate. Timepoint: Zero, second, fourth and eighth week. Method of measurement: questionnaire. Flaking. Timepoint: The second, fourth and eighth weeks. Method of measurement: questionnaire. Mazandaran University of Medical Sciences Approved 2018-08-18 Ethics committee of Mazandaran University of Medical Sciences Central headquarters of Mazandaran University of Medical Sciences and Health Services,beginning of Valiasr highway, Sari Mazandaran Iran (Islamic Republic of)