<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20210305050581N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2021-04-15</date_registration>
      <primary_sponsor>Riphah international university</primary_sponsor>
      <public_title>COMPARISON OF ACTIVE RELEASE TECHNIQUE AND POST ISOMETRIC RELAXATION TECHNIQUE IN NON-SPECIFIC NECK PAIN</public_title>
      <acronym></acronym>
      <scientific_title>COMPARISON OF ACTIVE RELEASE TECHNIQUE AND POST ISOMETRIC RELAXATION TECHNIQUE IN NON-SPECIFIC NECK PAIN</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2642-03-25</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>54</target_size>
      <recruitment_status>Pending</recruitment_status>
      <url>https://irct.ir/trial/54827</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: subjects will be randomly distributed (consecutive sampling) to two groups with the use of lottery method of randomization, group 1 patients will get ART, and group 2 will get post isometric relaxation technique, double-blind,, Blinding description: outcome assessor is not blind , the participant was blind, the therapist was blind, statistician was blind.</study_design>
      <phase>N/A</phase>
      <hc_freetext>non specific neck pain.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group1: active release technique, Both groups of patients received cervical isometrics, massage, and a hot pack for 10 minutes. Following that, both groups receive their respective treatments, i.e. Group A is given active release technique, in which the therapist examines and traps the MTrp of the affected muscle by applying pressure with his or her thumb or finger. After that, the patient was asked to actively shift from a reduced to an extended position. The therapist applied constant pressure and tension to the MTrps during this time.. While applying pressure to the ART patient, he or she was sitting or lying on the treatment table. Intervention 2: Intervention group2: post isometric relaxation technique, Group B was given a post-isometric relaxation technique. To perform this technique,The hypertonic muscle is taken to the point where resistance to movement becomes apparent, or to a duration just short of discomfort. A submaximal (10-20%) contraction of the hypertonic muscle is performed away from the limit for 5 to 10 seconds, while the therapist applies resistance in the opposite direction. During this effort, the patient should inhale. Following the isometric contraction, the patient is instructed to relax while exhaling. Following that, a gentle stretch is used to take up the slack until the new barrier is reached. The procedure is repeated beginning with this new barrier. Patients were evaluated prior to the first session and two weeks later using outcome measuring tools such as the NDI and the numeric pain rating scale to assess function and pain.Patients received two treatment sessions per week and were reassessed after the second week of treatment. Subjects did 7–10 repetitions of exercises three times a day, depending on pain intensity. The preliminary evaluation and treatment lasted one hour, and the subsequent treatments lasted 30–45 minutes. The subjects were given a maximum of four treatments over the course of two weeks.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is there is no further information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Dr. Taqdees Manzoor</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>H # 86/29 St # 30 Sunny View Park</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54810</zip>
        <telephone>+92 542 538127</telephone>
        <email>taqdeeskanwal13@gmail.com</email>
        <affiliation>Riphah international university</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Dr. Taqdees Manzoor</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>H # 86/29 St # 30 Sunny View Park</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54810</zip>
        <telephone>+92 542 538127</telephone>
        <email>taqdeeskanwal13@gmail.com</email>
        <affiliation>Riphah international university</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>•	Age range of 18 to 40 years
•	Both males and females
•	 Trigger points
•	Presence of taut bands in skeletal muscles
•	Limitation of neck movement due to pain
•	A minimum of two hours a day of computer usage or persistent (bending posture) work routine
•	Minimum of four weeks of neck pain due to TrPs in the muscles.</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>40 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>•	History of a whiplash injury,
Cervical spine surgery
•	Cervical radiculopathy , as diagnosed by their primary care physicians
•	Cervical spine fracture
•	Malignancy
•	Infection
•	Inflammatory disorder</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M54.2</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Cervicalgia</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Other</i_code>
      <i_code>Treatment - Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group1: active release technique, Both groups of patients received cervical isometrics, massage, and a hot pack for 10 minutes. Following that, both groups receive their respective treatments, i.e. Group A is given active release technique, in which the therapist examines and traps the MTrp of the affected muscle by applying pressure with his or her thumb or finger. After that, the patient was asked to actively shift from a reduced to an extended position. The therapist applied constant pressure and tension to the MTrps during this time.. While applying pressure to the ART patient, he or she was sitting or lying on the treatment table</i_keyword>
      <i_keyword>Intervention group2: post isometric relaxation technique, Group B was given a post-isometric relaxation technique. To perform this technique,The hypertonic muscle is taken to the point where resistance to movement becomes apparent, or to a duration just short of discomfort. A submaximal (10-20%) contraction of the hypertonic muscle is performed away from the limit for 5 to 10 seconds, while the therapist applies resistance in the opposite direction. During this effort, the patient should inhale. Following the isometric contraction, the patient is instructed to relax while exhaling. Following that, a gentle stretch is used to take up the slack until the new barrier is reached. The procedure is repeated beginning with this new barrier. Patients were evaluated prior to the first session and two weeks later using outcome measuring tools such as the NDI and the numeric pain rating scale to assess function and pain.Patients received two treatment sessions per week and were reassessed after the second week of treatment. Subjects did 7–10 repetitions of exercises three times a day, depending on pain intensity. The preliminary evaluation and treatment lasted one hour, and the subsequent treatments lasted 30–45 minutes. The subjects were given a maximum of four treatments over the course of two weeks.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Pain. Timepoint: Before treatment and after 2 weeks after treatment. Method of measurement: Numeric pain rating scale(NPRS),.</prim_outcome>
      <prim_outcome>Disability. Timepoint: Before treatment and after 2 weeks after treatment. Method of measurement: Neck disability index (NDI).</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Riphah international university</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2020-03-27</approval_date>
        <contact_name>Riphah ethical committee</contact_name>
        <contact_address>H # 86/29 St # 30 Sunny View Park Lahore Punjab Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
