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IRCT20210426051087N1 IRCT 2021-06-11 Islamic Azad University The effect of combined rehabilitation exercises in patients with coronary artery bypass grafting The effect of a combined training session on ABCA5 and ApoB gene expression and white blood cell lipid profile in middle-aged men after cardiac bypass surgery 2020-04-20 anticipated 60 Complete https://irct.ir/trial/55845 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: In fact, this study was performed to investigate the effect of endurance and resistance training on the physiological status of patients with coronary artery bypass grafting, Randomization description: The samples will be determined by random blocking method with 4 blocks using the table of random numbers of Software Allocation Random software. Blocking and allocation sequencing for concealment will be done by the person not involved in the research. 3 Chronic ischaemic heart disease, unspecified. Intervention 1: Intervention group: Aerobic-resistance training group. After taking blood samples and functional tests (5-second unassisted sit-up test (TUG), 3-meter back and forth (BBS) and cardiorespiratory function (6-minute walk)), participants are asked Start the training session with an aerobic program in three parts: walking on a treadmill (20 to 30 minutes), cycling (10 to 12 minutes) and manual ergometer (10 minutes) with an intensity of 60% of maximum heart rate. Then, by performing a resistance training program in three consecutive sets with 8 to 15 repetitions, the training session ends. The intensity of resistance training can be changed by using different colors (yellow to pink) of Traband. Then, at the end of the training period, blood is taken again and the functional test is measured again. Intervention 2: Intervention group: Resistance-aerobic training group. After taking blood samples and functional tests (5-second unassisted sit-up test (TUG), 3-meter back and forth (BBS) and cardiorespiratory function (6-minute walk)) from participants Is asked to Perform resistance training program in three consecutive sets with 8 to 15 repetitions. The intensity of resistance training can be changed by using different colors (yellow to pink) of Traband. Then the training session is completed with an aerobic program in three parts that included walking on a treadmill (20 to 30 minutes), pedaling on a bicycle (10 to 12 minutes) and hand ergometer (10 minutes) with an intensity of 60% of maximum heart rate. Also, at the end of the training period, blood is taken again and the functional test is measured again. Intervention 3: Control group: did not have any sports activities and supplementation and illegal drugs during the research protocol. No - There is not a plan to make this available Justification or reason for not sharing IPD is We apologize for publishing the data because of the ethical commitment it has made to patients and the Patient Rehabilitation Center.
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Mashhad Iran (Islamic Republic of) 917861311 +98 51 3880 3000 m_akbary64@hotmail.com Islamic Azad University Iran (Islamic Republic of) Age range 50-60 years Willingness to participate in research Cognitive, visual and auditory health No systolic blood pressure higher than 160 mmHg and diastolic blood pressure higher than 100 mmHg No acute and advanced diseases that prevent the exercises considered in this study. 50 years 60 years Male Existence of symptoms and heart failure Taking over-the-counter medications Inability to perform sports activities I25.7 Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris Prevention Prevention Prevention Intervention group: Aerobic-resistance training group. After taking blood samples and functional tests (5-second unassisted sit-up test (TUG), 3-meter back and forth (BBS) and cardiorespiratory function (6-minute walk)), participants are asked Start the training session with an aerobic program in three parts: walking on a treadmill (20 to 30 minutes), cycling (10 to 12 minutes) and manual ergometer (10 minutes) with an intensity of 60% of maximum heart rate. Then, by performing a resistance training program in three consecutive sets with 8 to 15 repetitions, the training session ends. The intensity of resistance training can be changed by using different colors (yellow to pink) of Traband. Then, at the end of the training period, blood is taken again and the functional test is measured again. Intervention group: Resistance-aerobic training group. After taking blood samples and functional tests (5-second unassisted sit-up test (TUG), 3-meter back and forth (BBS) and cardiorespiratory function (6-minute walk)) from participants Is asked to Perform resistance training program in three consecutive sets with 8 to 15 repetitions. The intensity of resistance training can be changed by using different colors (yellow to pink) of Traband. Then the training session is completed with an aerobic program in three parts that included walking on a treadmill (20 to 30 minutes), pedaling on a bicycle (10 to 12 minutes) and hand ergometer (10 minutes) with an intensity of 60% of maximum heart rate. Also, at the end of the training period, blood is taken again and the functional test is measured again. Control group: did not have any sports activities and supplementation and illegal drugs during the research protocol ABCG5 gene expression. Timepoint: 24 hours before the start of the protocol and 48 hours after the end of the last training protocol session. Method of measurement: REAL TIME-PCR method. APOB plasma levels. Timepoint: 24 hours before the start of the protocol and 48 hours after the end of the last training protocol session. Method of measurement: ELISA laboratory method. LDL plasma levels. Timepoint: 24 hours before the start of the protocol and 48 hours after the end of the last training protocol session. Method of measurement: ELISA laboratory method. Islamic Azad University Approved 2020-09-24 Ethics Committee of Islamic Azad University, Neyshabour Branch RESEARCH Ave, Islamic Azad University Complex Neyshabur Branch neyshabur Razavi Khorasan Iran (Islamic Republic of)