<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20210330050789N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2021-07-21</date_registration>
      <primary_sponsor>Riphah International University Lahore</primary_sponsor>
      <public_title>Comparison of hip strengthening exercises and knee exercises on pain, muscle strength and function in runners with knee pain</public_title>
      <acronym></acronym>
      <scientific_title>Comparison of specific hip strengthening exercises and conventional knee exercises on pain, muscle strength and function in sprinters with patello-femoral pain syndrome</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2021-08-01</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>28</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/57115</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Non probability convenient sampling technique will be used for recruitment of data. At the time of group allocation Sample will be randomly allocated into groups through lottery method. Another person from outside will be called out for sample allocation to groups and that person will be unaware of treatment of groups, Blinding description: An outcome accessor who will be unaware of the treatment of groups will take baseline pre and post measurements.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Patello-Femoral pain syndrome (PFPS) or anterior knee pain can be defined as retropatellar pain during stairs, hopping/jogging, prolonged sitting, kneeling, squatting or pain on palpation of patellar facets, femoral condyles. Patello femoral pain syndrome is also called as "runner's knee" because it is common in people who participate in sports, PFPS is the most prevalent orthopedic condition seen in sports medicine and it is the primary diagnosis in about 25% of all running injuries..</hc_freetext>
      <i_freetext>Intervention 1: Intervention group 1: conventional knee exercises and weight bearing hip strengthening exercise                     Conventional knee exercises are Squatting(0 to 45 degree/3 sets, 10 repetitions), Seated knee extension (90˚- 45˚/3 sets,10 repetitions) , Prone knee flexion (0˚- 90˚ / 3 sets,10 repetition), Single leg calf raise (3 sets 10 repetition). Stretching for quadriceps, hamstring, Iliotibial band (3 repetitions with 15 sec hold).  Weight bearing Hip strengthening exercises are Single leg Glute bridge (12 reps each side, 3 sets),  hip extension with knee flexion in quadruped position on shoulders( 12 reps each side, 3 sets), hip extension with knee extension in quadruped position on shoulder ( 12 reps on each side, 3 sets), side lying hip abduction ( 12 reps on each side, 3 sets)                                                         All exercises will be performed 3 times a week on alternate days for 6 weeks                                              Pain will be recorded by NPRS, Muscle Strength will be measured by dynamometer and function will be measured by Anterior Knee Pain Scale Questionnaire(AKPS) All outcome measures will be recorded before intervention and 6 weeks after intervention. Intervention 2: Intervention group 2: Conventional knee exercises and hip strengthening exercise with resistance.          Conventional knee exercises are Squatting(0 to 45 degree/3 sets, 10 repetitions), Seated knee extension (90˚- 45˚/3 sets,10 repetitions) , Prone knee flexion (0˚- 90˚ / 3 sets,10 repetition), Single leg calf raise (3 sets 10 repetition). Stretching for quadriceps, hamstring, Iliotibial band (3 repetitions with 15 sec hold).  Hip strengthening exercises with resistance are Single leg Glute bridge with resistance(12 reps each side, 3 sets),  hip extension with knee flexion in quadruped position on shoulders with resistance( 12 reps each side, 3 sets), hip extension with knee extension in quadruped position on shoulder with resistance( 12 reps on each side, 3 sets), side lying hip abduction with resistance( 12 reps on each side, 3 sets) For resistance, resistance band/loop band will be used                                                                                                    All exercises will be performed 3 times a week on alternate days for 6 weeks                                              Pain will be recorded by NPRS, Muscle Strength will be measured by dynamometer and function will be measured by Anterior Knee Pain Scale Questionnaire(AKPS) All outcome measures will be recorded before intervention and 6 weeks after intervention.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>No - There is not a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for not sharing IPD is There is no further information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Mahnoor Asif</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>House No 494 Block 2 Sector C1 Township</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54000</zip>
        <telephone>+92 42 35465074</telephone>
        <email>mahamasif96@gmail.com</email>
        <affiliation>REX Clinic, Model town, Lahore Pakistan</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Mahnoor Asif</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>House No 494 Block 2 Sector C1 Township</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54000</zip>
        <telephone>+92 42 35465074</telephone>
        <email>mahamasif96@gmail.com</email>
        <affiliation>REX Clinic, Model Town, Lahore</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Positive patellar compression test
Subjects having anterior knee pain for least 4 weeks
Muscle power for quadriceps, hamstring, gluteus medius and gluteus maximus should be grade 3
Pain aggravates during any of the following two activities like ascending &amp; descending stairs, squatting, kneeling, jumping, running, jogging
Average pain level of 3-cm or more on a 10-cm Numerical pain rating scale</inclusion_criteria>
      <agemin>15 years</agemin>
      <agemax>30 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>neurological disorder
Injury to lumbosacral region, hip or ankle
Rheumatoid arthritis
Pregnancy
Patellar instability
history of knee injury
signs or symptoms of other pathology
recent history (within 3 months) of knee surgery
history of patellar dislocation/subluxation
clinical evidence of meniscal lesion, ligamentous instability, patellar tendon pathology, chondral damage, osteoarthritis, or referred pain from the spine.</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M25.56</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Pain in knee</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group 1: conventional knee exercises and weight bearing hip strengthening exercise                     Conventional knee exercises are Squatting(0 to 45 degree/3 sets, 10 repetitions), Seated knee extension (90˚- 45˚/3 sets,10 repetitions) , Prone knee flexion (0˚- 90˚ / 3 sets,10 repetition), Single leg calf raise (3 sets 10 repetition). Stretching for quadriceps, hamstring, Iliotibial band (3 repetitions with 15 sec hold).  Weight bearing Hip strengthening exercises are Single leg Glute bridge (12 reps each side, 3 sets),  hip extension with knee flexion in quadruped position on shoulders( 12 reps each side, 3 sets), hip extension with knee extension in quadruped position on shoulder ( 12 reps on each side, 3 sets), side lying hip abduction ( 12 reps on each side, 3 sets)                                                         All exercises will be performed 3 times a week on alternate days for 6 weeks                                              Pain will be recorded by NPRS, Muscle Strength will be measured by dynamometer and function will be measured by Anterior Knee Pain Scale Questionnaire(AKPS) All outcome measures will be recorded before intervention and 6 weeks after intervention</i_keyword>
      <i_keyword>Intervention group 2: Conventional knee exercises and hip strengthening exercise with resistance.          Conventional knee exercises are Squatting(0 to 45 degree/3 sets, 10 repetitions), Seated knee extension (90˚- 45˚/3 sets,10 repetitions) , Prone knee flexion (0˚- 90˚ / 3 sets,10 repetition), Single leg calf raise (3 sets 10 repetition). Stretching for quadriceps, hamstring, Iliotibial band (3 repetitions with 15 sec hold).  Hip strengthening exercises with resistance are Single leg Glute bridge with resistance(12 reps each side, 3 sets),  hip extension with knee flexion in quadruped position on shoulders with resistance( 12 reps each side, 3 sets), hip extension with knee extension in quadruped position on shoulder with resistance( 12 reps on each side, 3 sets), side lying hip abduction with resistance( 12 reps on each side, 3 sets) For resistance, resistance band/loop band will be used                                                                                                    All exercises will be performed 3 times a week on alternate days for 6 weeks                                              Pain will be recorded by NPRS, Muscle Strength will be measured by dynamometer and function will be measured by Anterior Knee Pain Scale Questionnaire(AKPS) All outcome measures will be recorded before intervention and 6 weeks after intervention.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Pain. Timepoint: Pain will be measured before intervention and 6 weeks after intervention. Method of measurement: Pain will be recorded through Numeric pain rating Scale(NPRS).</prim_outcome>
      <prim_outcome>Muscle Strength. Timepoint: Muscle Strength will be measured before intervention and 6 weeks after intervention. Method of measurement: Muscle Strength will be measured by Dynamometer.</prim_outcome>
      <prim_outcome>Knee Function. Timepoint: Function will be measured before intervention and 6 weeks after intervention. Method of measurement: Function will be measured by Anterior Knee Pain Scale Questionnaire.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Self funded</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2021-06-14</approval_date>
        <contact_name>Research &amp; Ethics Committee of Riphah International University Lahore, Pakistan</contact_name>
        <contact_address>House No 494 Block 2 Sector C1 Township Lahore Punjab Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
