<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20200611047734N4</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2021-10-13</date_registration>
      <primary_sponsor>university of Lahore, Lahore</primary_sponsor>
      <public_title>The comparative effects of Butler’s neural tissue mobilization and Mulligan’s bent leg raise  in patients with chronic lumbar radiculopathy.</public_title>
      <acronym></acronym>
      <scientific_title>The comparative effects of Butler’s neural tissue mobilization and Mulligan’s bent leg raise  in patients with chronic lumbar radiculopathy.</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2020-06-28</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>62</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/58678</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Parallel groups, single blinded, single setting, Randomization description: The lottery method was used for allocating the patient in groups A or B by even and odd numbers. Participants with an even number were placed in group A and with an odd number were placed in group B, Blinding description: It was a single-blinded study in which participant/ patients were kept blind for treatment technique. 2 different technique were provided to patients. and they were blind about that which technique was given to which patients. patients were blind regarding the technique. baseline treatment was the same, but they were not aware of the technique. which techniques they were receiving.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Lumber Radiculopathy.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: Application of conventional therapy and Butler neural tissue mobilization. Butler neural tissue mobilization procedure: Patient was in supine position. Therapist’s position was standing and facing towards the patient position and positioned one hand beneath the ankle to prevent pressure on peripheral nerves and the second hand above the patella. The knee was in extended position, and hip was flexed position in one plane and the leg was take to the point where symptoms was reproduced. Dosage: Slow oscillations or sustained stretch was given by the therapist for 10 s depending on the grade of mobilization after which the leg was returned to a non-painful position. This procedure was repeated three times. Intervention 2: Intervention group: Application of conventional therapy and Mulligan bent leg raise. Mulligan bent leg raise Technique. The therapist was stand at limited SLR side of the patient. Patients was flex knee was kept over therapist’s shoulder. Therapist instructed patient to push her away with patient’s leg and then relax. At this point therapist extended the patient’s bent knee up as far as possible in the direction of patient’s ipsilateral shoulder provided there was no pain. If it was painful the direction was altered by taking the leg more medially or laterally. Dosage: Sustained stretch for several seconds was given and leg lowered down to the bed. This technique was repeated 3 times.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
The comparative effects of Butler’s neural tissue mobilization and Mulligan’s bent leg raise in patients with chronic lumbar radiculopathy.

When:
The study is completed and become available after its publication

To whom:
Person in academic institute. Patient data will not be shown

Conditions:
Under the usage with terms in which journal is accessed /processed for publication, it could be used in the request.

Where to obtain:
+923367595206 from the University office and Responsible supervisor and from a journal we will process in future

How to obtain:
Can be on call or mail It will be only used in a confidential way for improving research and benefit of humanity

Comments:
Data can be provided on request</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Sonia Yasmeen</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Raiwind road lahore</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>55150</zip>
        <telephone>+92 42 32591427</telephone>
        <email>soniayasmeen16@gmail.com</email>
        <affiliation>university of Lahore, Lahore</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Fareeha Amjad</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Raiwind road lahore</address>
        <city>LAHORE</city>
        <country1>Pakistan</country1>
        <zip>55150</zip>
        <telephone>+92 42 32591427</telephone>
        <email>fari_fairy22@yahoo.com</email>
        <affiliation>university of Lahore, Lahore</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Patients diagnosed with lumber radiculopathy with unilateral radiating pain by an orthopedics
Age 25-50 years
Both Male and Female
Positive neurodynamic test i.e.  SLR test and Slump test</inclusion_criteria>
      <agemin>25 years</agemin>
      <agemax>50 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Patients having Somatic referred pain
Specific diseases of spine like ankylosing spondylitis, paget’s disease, vertebral collapse, rheumatoid arthritis, and spondylolisthesis
Tb spine, intermittent claudication, diabetic neuropathy
Recent infection
Mental retardation
hemiparesis
previous spinal Surgery
Pelvis Fracture
Pregnancy
Red Flags such as trauma, cancer, constitutional symptoms (fever, malaise, weight loss)</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M47.26</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Other spondylosis with radiculopathy, lumbar region</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Devices</i_code>
      <i_code>Treatment - Devices</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: Application of conventional therapy and Butler neural tissue mobilization. Butler neural tissue mobilization procedure: Patient was in supine position. Therapist’s position was standing and facing towards the patient position and positioned one hand beneath the ankle to prevent pressure on peripheral nerves and the second hand above the patella. The knee was in extended position, and hip was flexed position in one plane and the leg was take to the point where symptoms was reproduced. Dosage: Slow oscillations or sustained stretch was given by the therapist for 10 s depending on the grade of mobilization after which the leg was returned to a non-painful position. This procedure was repeated three times.</i_keyword>
      <i_keyword>Intervention group: Application of conventional therapy and Mulligan bent leg raise. Mulligan bent leg raise Technique. The therapist was stand at limited SLR side of the patient. Patients was flex knee was kept over therapist’s shoulder. Therapist instructed patient to push her away with patient’s leg and then relax. At this point therapist extended the patient’s bent knee up as far as possible in the direction of patient’s ipsilateral shoulder provided there was no pain. If it was painful the direction was altered by taking the leg more medially or laterally. Dosage: Sustained stretch for several seconds was given and leg lowered down to the bed. This technique was repeated 3 times.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Pain. Timepoint: pre and post treatment. Method of measurement: Numeric pain rating scale.</prim_outcome>
      <prim_outcome>ROM (lumber flexion, extension, SLR). Timepoint: Pre and post treatment. Method of measurement: Goniometer , Modified Modified Schober’s Test.</prim_outcome>
      <prim_outcome>Functional Disability. Timepoint: pre and post treatment. Method of measurement: Oswestry Disability Index.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>university of Lahore, Lahore</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2020-06-28</approval_date>
        <contact_name>Institutional Review Board</contact_name>
        <contact_address>Raiwind road Lahore Punjab Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
