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IRCT20200901048586N1 IRCT 2021-12-09 Iran University of Medical Sciences Evaluation of the impact of adipose tissue stem cells on the effectiveness of fat particles injection, prepared from patient's adipose tissue, in the treatment of ŮŽAcne scars Evaluation of the effectiveness of stromal vascular fraction cells in the impact of Nanofat on acne scar 2021-11-22 anticipated 10 Complete https://irct.ir/trial/59835 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Randomization description: Randomly blinded clinical trial Nanofat cells are injected into scars on both sides of the face and SVF cells are injected randomly into scars on only one side of the face, Blinding description: In this study, acne scars on both sides of the face are treated with Nanofat injection. However, SVF injections are performed randomly on only one side, and the patient does not know which side the SVF injection is in. N/A Condition 1: Acne scar. Condition 2: Acne scar. Control group: In these patients, after preparing SVF and Nanoft by taking 100 ccs fat from the thigh area, the scars on one side of the face are treated with only Nanofat. However, the scars on the other side are treated with Nanoft and SVF both together. The part of the face that was treated with Nanoft alone is the control group. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no more information
public Sepideh Moradi
No. 2, Unit 3, Shahid Jafari Alley, 3rd Dashtestan St., Pasdaran St.
Tehran Iran (Islamic Republic of) 1947948584 +98 21 2284 1683 sepideh.moradi1989@gmail.com Iran University of Medical Sciences scientific Sepideh moradi
No. 2, Unit 3, Shahid Jafari Alley, 3rd Dashtestan St., Pasdaran St.
Tehran Iran (Islamic Republic of) 1947948584 +98 21 2284 1683 sepideh.moradi1989@gmail.com Iran University of Medical Sciences Iran (Islamic Republic of) The patient has the informed consent to participate in the study. The patient should be able to participate regularly at all appointments and follow-up sessions. The patient should not have any serious internal disease. The patient should not have accompanying disease on the treatment site. 18 years 50 years Both Taking anticoagulants and steroids Existence of active skin or systemic infection Having a malignancy or a history of receiving chemotherapy medications Breastfeeding or pregnancy History of receiving any analgesic medications during the week before of the intervention L70 Acne Treatment - Other Control group: In these patients, after preparing SVF and Nanoft by taking 100 ccs fat from the thigh area, the scars on one side of the face are treated with only Nanofat. However, the scars on the other side are treated with Nanoft and SVF both together. The part of the face that was treated with Nanoft alone is the control group In all patients, the initial grade of acne scar is qualitatively determined based on the Goodman and Baron grading system (grade 1 grade 2 grade 3 grade 4). Timepoint: Acne scar Examination before the intervention is one month and then three months later. Method of measurement: 1) Scar size change evaluation based on digital re-imaging, 2)Evaluating the extent of Neoclagenesis by ultrasound. Iran University of Medical Sciences Approved 2020-07-28 Ethics committee of Iran university of Medical Sciences Iran University of Medical Sciences, Tehran, Iran Tehran Tehran Iran (Islamic Republic of) Approved 2020-09-26 Ethics committee of Iran university of Medical Sciences Iran University of Medical Sciences, Tehran, Iran Tehran Tehran Iran (Islamic Republic of)