<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20220209053982N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2022-03-14</date_registration>
      <primary_sponsor>Abadan University of Medical Sciences</primary_sponsor>
      <public_title>"The effect of aerobic and resistance training on patients improved from COVID-19"</public_title>
      <acronym></acronym>
      <scientific_title>The effect of eight weeks of selected aerobic and resistance training on myokine profile of patients improved from COVID-19</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2022-04-09</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>33</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/62060</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Supportive, Other design features: First, the sample individuals are selected voluntarily based on the inclusion criteria and then randomly divided into three groups: aerobic training, resistance training and control, Randomization description: First, in Abadan and Khorramshahr counties, and then among the people who announce their readiness, 33 people are selected voluntarily based on the inclusion criteria and are randomly divided into three groups. In the simple random method, each person is assigned a number, then the folded sheets, which include the number of each person, are placed in a container, and based on the lottery, the above numbers are arranged in three groups of selected aerobic exercises (11 people). ), Selected resistance exercises (11 people) and the control group (11 people).</study_design>
      <phase>N/A</phase>
      <hc_freetext>COVID-19.</hc_freetext>
      <i_freetext>Intervention 1: Aerobic exercise group: Exercises including running with an intensity of 50 to 70% of maximum heart rate, three sessions per week for eight weeks located in the gym of the Islamic Azad University, Abadan Branch. Intervention 2: Resistance training group: Exercises including eight movements of chest press, squat, forearm, leg press, back arm, front thigh, boat and back with intensity of 40 to 75% of a maximum repetition, three sessions per week for eight weeks in the gym Islamic Azad University, Abadan Branch will be implemented. Intervention 3: Control group: does not receive any of these training interventions and their status will be followed up by phone and in person.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is There is no more information</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Parisa Amiri Farsani</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>No. 16, Arghavan Alley, Professors' Alley, University of Marine Sciences and Technology, Ali Ibn Abitaleb Boulevard</address>
        <city>Khorramshahr</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>64199-34619</zip>
        <telephone>+98 61 5353 1938</telephone>
        <email>parisaamirif@yahoo.com</email>
        <affiliation>Islamic Azad University, Science and Research Branch of Tehran</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Farshad Ghazalian</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Islamic Azad University, Science and Research Branch, Shohada Hesarak Blvd., University Square, End of Shahid Sattari Highway</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1477893855</zip>
        <telephone>+98 21 44865154-8</telephone>
        <email>phdghazalian@gmail.com</email>
        <affiliation>Islamic Azad University, Science and Research Branch of Tehran</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>People recovering from COVID-19
Women in the age range of 20 to 45 years
No other medical problems including cardiovascular disease, chronic liver, kidney, gastrointestinal disease, immune deficiency, chronic inflammatory disease and metabolic diseases
Lack of muscle, joint and orthopedic problems that prevent exercise</inclusion_criteria>
      <agemin>20 years</agemin>
      <agemax>45 years</agemax>
      <gender>Female</gender>
      <exclusion_criteria>Pregnancy
Having been active in sports for the past year
taking medication</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>U07.1</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>COVID-19 disease</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Rehabilitation</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Aerobic exercise group: Exercises including running with an intensity of 50 to 70% of maximum heart rate, three sessions per week for eight weeks located in the gym of the Islamic Azad University, Abadan Branch.</i_keyword>
      <i_keyword>Resistance training group: Exercises including eight movements of chest press, squat, forearm, leg press, back arm, front thigh, boat and back with intensity of 40 to 75% of a maximum repetition, three sessions per week for eight weeks in the gym Islamic Azad University, Abadan Branch will be implemented.</i_keyword>
      <i_keyword>Control group: does not receive any of these training interventions and their status will be followed up by phone and in person.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Plasma levels of irisin. Timepoint: One day before the start of training protocols and forty-eight hours after the last training session. Method of measurement: Special irisin measurement kit.</prim_outcome>
      <prim_outcome>Plasma levels of FGF21. Timepoint: One day before the start of training protocols and forty-eight hours after the last training session. Method of measurement: Special FGF21 measurement kit.</prim_outcome>
      <prim_outcome>Plasma levels of folistatin. Timepoint: One day before the start of training protocols and forty-eight hours after the last training session. Method of measurement: Special follicatin measurement kit.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Body mass index: It is a suitable measure for estimating the health of a person's weight according to height. Timepoint: Before and after the intervention. Method of measurement: By calculating height and weight.</sec_outcome>
      <sec_outcome>Maximum oxygen consumption: is the maximum amount of oxygen consumed by a person per kilogram of body weight in one minute. Timepoint: Before and after the intervention. Method of measurement: Rockport Walk Test.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Abadan University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2022-02-06</approval_date>
        <contact_name>Ethics Committee of Abadan University of Medical Sciences</contact_name>
        <contact_address>The beginning of 30 meters of Zolfaghari Abadan Khouzestan Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
