<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20220825055791N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2022-09-15</date_registration>
      <primary_sponsor>Govt. college university of Faisalabad</primary_sponsor>
      <public_title>effect of active cycle of breathing techniques (ACBT)  in covid-19 patients</public_title>
      <acronym></acronym>
      <scientific_title>Assessment of effect of active cycle of breathing techniques (ACBT) on airway clearance in covid-19 patients</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2022-04-24</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>100</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/65554</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment, Other design features: One hundred COVID-19 patients, age group 30-60 years from both indoor and ICU were involved in this research.</study_design>
      <phase>3</phase>
      <hc_freetext>In this research Coronavirus (COVID-19) pandemic was studied.  Patients with Obstructive pulmonary disease that is corona was studied to observe the ACBT treatment plan. Previous studies have shown that incidence of COVID-19 has increased more effectively among both gender ranges from 43% male and 57% female. Approximately, major population suffered with COVID-19 report fever, shortness of breath, cough, tachypnea, chest tightness, dyspnea, chills, high-grade temperature and even death..</hc_freetext>
      <i_freetext>Intervention 1: Control group: COVID-19 population was targeted. Total 100 patients were taken. In this study pre and post vitals and required information history was taken. 2 groups was involved. One group is labelled as pre- group with no intervention applied and severe COVID-19 symptoms. The prior vitals then compared with post vitals after 2 weeks of  treatment application to check outcome results. Procedure repeated 2- times a week. Treatment method was Active cycle of breathing techniques, use to reduced the pulmonary symptoms. Intervention 2: Intervention group: COVID-19 population was targeted. Total 100 patients were taken. 2nd group was labelled as Post- group and vitals and required information history was taken after 2 weeks of  treatment application to check outcome results. Procedure repeated 2- times a week. Treatment method was Active cycle of breathing techniques, use to reduced the pulmonary symptoms. results compared to the prior vitals were 96% more satisfactory and ACBT proved beneficial for airway clearance in COVID-19 patients.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Yes - There is a plan to make this available</results_IPD_plan>
      <results_IPD_description>What will be shared:
Assessment of effect of active cycle of breathing techniques (ACBT) on airway clearance in covid-19 patients

When:
starting 6 months after publication.

To whom:
This only available for people working in academic institutions or people working in businesses can also apply to receive it.

Conditions:
it is an cosile study and researchers can approach this article by simply entering the MESH keys.

Where to obtain:
For communication means contact anamyousaf13@gmail.com.

How to obtain:
contact via mail or number mentioned.

Comments:
</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Anam Yousaf</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>street no. 05, khadim colony, shahdara, lahore.</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>street no. 05, khadi</zip>
        <telephone>+92 310 4722300</telephone>
        <email>anamyousaf13@gmail.com</email>
        <affiliation>Govt. college university of Faisalabad</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Anam Yousaf</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>street no. 05, khadim colony, shahdara, lahore.</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>street no. 05, khadi</zip>
        <telephone>+92 310 7722300</telephone>
        <email>anamyousaf13@gmail.com</email>
        <affiliation>Govt. college university of Faisalabad</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Patients having the age range from 30-60 were selected.
Patients who were admitted to ICU or COVID indoor patients were included.
Patients who were conscious were selected for this study.</inclusion_criteria>
      <agemin>30 years</agemin>
      <agemax>60 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Individuals below age 30, without COVID or with other comorbidities were prohibited from our review.
Patients with decreased awareness and conscious level were not included in the assortment criteria.
Patients admitted to CCU were excluded.</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>U07</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>COVID-19, virus identified</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Other</i_code>
      <i_code>Treatment - Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Control group: COVID-19 population was targeted. Total 100 patients were taken. In this study pre and post vitals and required information history was taken. 2 groups was involved. One group is labelled as pre- group with no intervention applied and severe COVID-19 symptoms. The prior vitals then compared with post vitals after 2 weeks of  treatment application to check outcome results. Procedure repeated 2- times a week. Treatment method was Active cycle of breathing techniques, use to reduced the pulmonary symptoms.</i_keyword>
      <i_keyword>Intervention group: COVID-19 population was targeted. Total 100 patients were taken. 2nd group was labelled as Post- group and vitals and required information history was taken after 2 weeks of  treatment application to check outcome results. Procedure repeated 2- times a week. Treatment method was Active cycle of breathing techniques, use to reduced the pulmonary symptoms. results compared to the prior vitals were 96% more satisfactory and ACBT proved beneficial for airway clearance in COVID-19 patients.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Pre outcomes were breathing rate 48 breath pre minute. After interventions application results were improved breathing rate was 16-20 breath pre minute which was like normal people. Timepoint: In this study patients were checked before and after the ACBT interventions applied. symptoms of berating compilation were assessed. cough, dyspnea, shortness of breath. The treatment application time was 2 weeks. Patient history was taken prior to treatment and after 2 weeks treatment plan. Method of measurement: The patient examination was performed before and after the treatment by using the tool Interventions Evaluation on COVID-19 patients-Questionnaire to assess the impact of Coronavirus on people and exercises effects on airways clearance.</prim_outcome>
      <prim_outcome>Temperature was raised up to (103F) which represents body immune system activation against virus or other foreign agent. after treatment application temperature reduced to optimal level that is 37F. Timepoint: In this study patients were checked before and after the ACBT interventions applied. Fever/pyrexia was the initial sign along with oxygen level during corona patient diagnosis. The treatment application time was 2 weeks. Patient history was taken prior to treatment and after 2 weeks treatment plan. Method of measurement: The patient examination was performed before and after the treatment by using the tool Interventions Evaluation on COVID-19 patients-Questionnaire to assess the impact of Coronavirus on people and exercises effects on airways clearance.</prim_outcome>
      <prim_outcome>O2 saturation was less than 75% -80% before treatment applied an after treatment application O2 improve to &gt;90%. ACBT proved more beneficial for COVID-19 patients. Timepoint: In this study patients were checked before and after the ACBT interventions applied. O2 saturation vital sign was  checked in corona patients every 24-hours because most deadly agent was oxygen vital. The treatment application time was 2 weeks. Patient history was taken prior to treatment and after 2 weeks treatment plan. Method of measurement: The patient examination was performed before and after the treatment by using the tool Interventions Evaluation on COVID-19 patients-Questionnaire to assess the impact of Coronavirus on people and exercises effects on airways clearance.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Govt. college university of Faisalabad</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2022-07-27</approval_date>
        <contact_name>Afro-Asian Institute</contact_name>
        <contact_address>43-52 Khayaban-e-Kareem Rd, Near  Nishter Metro Station Lahore Punjab Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
