IRCT20211225053519N3 IRCT 2023-10-24 Tehran University of Medical Sciences Dexmedetomidine in rhinoplasty Evaluation of the effect of dexmedetomedine as a adjuvant drug for local anesthesia infiltration on the rate of interaoperative bleeding and pain relief after septorhinoplasty 2023-10-22 anticipated 42 Complete https://irct.ir/trial/73166 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: In this study, we will use the block randomization method. Blocking is usually used to balance the number of samples assigned to each study group. The size of all the blocks in this study is equal, and we will have a 4-person block size (two interventions and two controls). Random allocation software is also used as the randomization tool. The allocation concealment will be used for hiding so that the assigned group is not known before the individual is assigned. Using opaque envelopes sealed with random sequences, each of the random sequences created is recorded on a card, and the cards are placed in the envelopes, respectively. To maintain a random series, the envelopes are numbered in the same way on the outer surface. Finally, the lids of the envelopes are glued and placed in a box, respectively. At the beginning of the registration of participants, based on the order of entry of eligible participants into the study, one of the envelopes of the letter is opened in order, and the assigned group of the participant is revealed, Blinding description: Each group will have a specific code and patients, outcome assessor, and data analyzer will not be informed of the intervention. 3 Pain after septorhinoplasty. Intervention 1: Intervention group: There will be patients in whom 8 ml of 2% lidocaine, 1 ml of adrenaline with a dilution of 1:100,000, and 1 ml of normal saline will be used for local anesthesia. Intervention 2: Intervention group: There will be patients in whom 8 ml of 2% lidocaine, 1 ml of adrenaline with 1:100,000 dilution, and 1 ml of dexmedetomidine will be used for local anesthesia. Yes - There is a plan to make this available What will be shared: All Deidentified Individual Participant Data Set will be available after the end of the study When: 6 months after publishing the results To whom: Researchers who work in an academic institute Conditions: Data is given to the researchers just for assessment and not for interfering Where to obtain: Through email: rezapurrokni@yahoo.com How to obtain: The data will given to researchers after assessing the eligibility through email Comments: