IRCT20240415061488N1 IRCT 2024-04-25 Bagheiat-allah University of Medical Sciences Evaluation of Betaxolol in improving the acute phase of patients with mild to moderate Traumatic Brain Injury Evaluation of Betaxolol in improving the Glasgow Outcome Scale Extended (GOSE) of the acute phase of patients with mild to moderate Traumatic Brain Injury: A double blinded randomized Clinical Trial 2024-05-21 anticipated 104 Complete https://irct.ir/trial/76399 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Patients are randomly assigned to two groups, intervention (A) and control (B), using a stratified block randomization method with block size of four. The classification and randomization are carried out by a research assistant who has no involvement in selecting patients or evaluating patient outcomes. Given the four-member block size, there are six possible configurations for patient allocation, such that two individuals are placed into the intervention group and two into the control group (for example, ABBA and BBAA). Patients are categorized by age into two groups: those under 40 years and those 40 years and older, with members of each age group divided into blocks of four. A random one of the six possible configurations is then selected for each block, placing patients in the designated groups accordingly. This process will continue until sample collection is complete, Blinding description: The same individual who carried out the randomization of patient selection also gives the drug or placebo of each patient to the researcher. Since the drug and placebo are identical in appearance, the researcher will not be able to distinguish between the two. The patient is also unaware of which one they are receiving. 3 Traumatic Brain Injury. Intervention 1: Intervention group: Taking Betaxolol Hydrochloride 5mg, Oral, Single Dose, This drug is given to the patients of the intervention group one time after admission to the hospital. Intervention 2: Control group: Taking placebo, Oral, Placebo is given to the patients of the control group one time after admission to the hospital. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is The team of this project has not yet decided what to do on this matter.