IRCT20240615062138N1 IRCT 2025-03-02 Shahid Beheshti University of Medical Sciences Effect of methylprednisolone pals in treatment of children with refractory epilepsy The efficasy of treatment with 5 days methylprednisolone pals on electroencephalography in children with refractory epilepsy . 2023-03-21 anticipated 50 Complete https://irct.ir/trial/77469 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 2 Refractory epilepsy. Intervention group:This intervention is conducted in patients based on the history and clinical examination of seizures and confirmed in the ideal state of the brain EEG. The method of working is that by diagnosing patients who refer to the Children's Neuroscience Clinic of Shohadaye Tajrish and Mofid Hospitals (based on the include and exclude criteria of the study) and in the sleep or wake of EEG, they obtain a written consent. They are then hospitalized in the neurological section of the children.As soon as the routine tests are hospitalized, infectious examination and electrolytes and kidney function are taken from the patient and if they do not have infectious issues and other exclusion at a dose of 20 mg / kg body weight methylprednisolon for 5 consecutive days in a row with vital symptoms and symptoms. Registration is injected regularly during the medication. Evaluated during hospitalization and third day. One day after receiving the last dose of the day, the EEG will be taken again in sleep or wake up. The patient will be discharged by age and gender after general recovery and seizures) in a number of anti -epithelials related to the type of seizures (and will be followed for 2 years in 6, 12,18 and 24 followed up. Clinical symptoms and seizures control, drug complications and EEG findings will be investigated.. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information