IRCT20240619062178N1 IRCT 2024-06-22 Shahid Beheshti University of Medical Sciences The effect of lidocaine infusion on pain reduction and the amount of opioid consumption after surgery The effect of lidocaine infusion during laparotomy surgery on the reduction of postoperative pain and the amount of opioid consumption to control postoperative pain. 2024-07-22 anticipated 60 Complete https://irct.ir/trial/77500 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: For randomization, a table of random numbers was used, in order to create a random sequence using a table of random numbers by a statistical consultant, the patients were randomly given one of the even and odd codes, the patients with even codes were placed in the first group and the odd codes were placed in the second group, Blinding description: Medicines in envelopes that are similar in appearance are labeled as group A and B. The patient does not know about this labeling, nor does the drug distributor's colleague know about the labeling. In order to avoid any possible complications, the main researcher is aware of the allocation of groups. 3 Laparotomy surgery. Intervention 1: Intervention group: After induction of anesthesia using midazolam fentanyl as premedication, propofol as hypnotic and etracorium as muscle relaxant, two minutes before intubation until surgical incision, administration of 1% lidocaine with a bolus dose of 1mg/kg is done as a slow intravenous injection. Then its infusion continues with a dose of 1mg/kg/h until the end of the operation. Intervention 2: Control group: In the control group, normal saline infusion is used instead of lidocaine. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information