<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20221205056713N3</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2024-07-26</date_registration>
      <primary_sponsor>Rashid Latif Medical college</primary_sponsor>
      <public_title>Effects of retro walking exercises and clamshell exercises in osteoarthritis</public_title>
      <acronym></acronym>
      <scientific_title>Combined Effects of Retro Walking Exercises and Clamshell Exercises on Pain, Strength and Balance among Osteoarthritis Patients</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2024-07-25</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>34</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/78115</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Participants will randomly divided in two groups (group A group B) by using lottery method. Both groups will be given conventional physical therapy treatment. Group A patients will be treated with the retro walking exercises and Group B patients will be treated with retro walking and clamshell exercises, Blinding description: Subjects in two groups will blinded from other treatment options. However they will be instructed to report any adverse effects during trial. Data will assessed by a third person which will not known about the study so trial will be single blinded study. (as outcome assessor will be blinded).</study_design>
      <phase>N/A</phase>
      <hc_freetext>Osteoarthritis of knee.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group:  Group will be treated with Clamshell exercise. we will take diagnosed patients of Osteoarthritis and perform clamshell walking exercises. Firstly patient is positioned in supine lying regular period of 6 days in a week for application of hot pack over knee for 10 min and start Clamshell walking in treadmill which includes clamshell walking two session per day (10 min per session) for 3 weeks on a treadmill at their maximum pace. The treatment duration will be 45 min in each session for a regular period of 6 days in a week. Both groups will receive hot pack for 10 min prior to exercise in order to warm up the muscle. Pre-test values will be taken on the first day and the post-test values will be taken after the total study duration of 3 week. Intervention 2: Intervention group: Group B will be treated with , we take diagnosed patients of osteoarthritis and performed clamshell exercises along with retro walking exercises. Firstly, apply hot pack for 10 minutes in order to warm up and for improvement of circulation in muscles. Then we will strengthen the gluteus-medius to-tensor-fasciae latae by performing the clamshell and abduction exercises. unilateral wall-squat showed a significantly greater Gluteus med/TFL activation, side-lying hip abduction with anterior log-rolling position showed significantly greater Gluteus med activation, side-lying hip abduction exercise, side bridge exercise with knee flexion strengthen the Gluteus med/TFL muscle activation ratio than side bridge exercise or side bridge exercise with knee flexion and hip abduction.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is It is not yet known if there will be a plan to make this available</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Sidra Ishaq</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>35-KM, Ferozepur Road. Lahore.</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54900</zip>
        <telephone>+92 321 1185253</telephone>
        <email>ishaqsidra8@gmail.com</email>
        <affiliation>Rashid Latif Medical College</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Hafiza Nida Rasheed</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>35-KM, Ferozepur Road. Lahore</address>
        <city>Lahore</city>
        <country1>Pakistan</country1>
        <zip>54900</zip>
        <telephone>+92 336 4535979</telephone>
        <email>naddia.rasheed20@gmail.com</email>
        <affiliation>Rashid Latif Medical College</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Pakistan</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Both genders male and female age above 40 years .
Patients diagnosed with OA and confirmed by radiographic imaging
History of knee pain in past 30 days</inclusion_criteria>
      <agemin>40 years</agemin>
      <agemax>no limit</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Patients diagnosed with rheumatoid arthritis
Having history of ankle or knee surgery
History of intra-articular injection in knee joint in past 1 year
Patients having dizziness or balance problems
Pregnant females</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M17</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Osteoarthritis of knee</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Treatment - Other</i_code>
      <i_code>Treatment - Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group:  Group will be treated with Clamshell exercise. we will take diagnosed patients of Osteoarthritis and perform clamshell walking exercises. Firstly patient is positioned in supine lying regular period of 6 days in a week for application of hot pack over knee for 10 min and start Clamshell walking in treadmill which includes clamshell walking two session per day (10 min per session) for 3 weeks on a treadmill at their maximum pace. The treatment duration will be 45 min in each session for a regular period of 6 days in a week. Both groups will receive hot pack for 10 min prior to exercise in order to warm up the muscle. Pre-test values will be taken on the first day and the post-test values will be taken after the total study duration of 3 week</i_keyword>
      <i_keyword>Intervention group: Group B will be treated with , we take diagnosed patients of osteoarthritis and performed clamshell exercises along with retro walking exercises. Firstly, apply hot pack for 10 minutes in order to warm up and for improvement of circulation in muscles. Then we will strengthen the gluteus-medius to-tensor-fasciae latae by performing the clamshell and abduction exercises. unilateral wall-squat showed a significantly greater Gluteus med/TFL activation, side-lying hip abduction with anterior log-rolling position showed significantly greater Gluteus med activation, side-lying hip abduction exercise, side bridge exercise with knee flexion strengthen the Gluteus med/TFL muscle activation ratio than side bridge exercise or side bridge exercise with knee flexion and hip abduction</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Pain. Timepoint: Before treatment and 4 weeks after treatment. Method of measurement: By using Numeric pain rating scale.</prim_outcome>
      <prim_outcome>Balance. Timepoint: Before treatment and 4 weeks after treatment. Method of measurement: By using Balance berg scale.</prim_outcome>
      <prim_outcome>Muscle strength. Timepoint: Before treatment and 4 weeks after treatment. Method of measurement: Sit to stand test.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome></sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Rashid Latif Medical college</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2023-10-10</approval_date>
        <contact_name>The institutional board of Rashid Latif Medical College, Lahore</contact_name>
        <contact_address>35KM Ferozepur Road, Lahore. Lahore  Pakistan</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
