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IRCT20240721062487N2 IRCT 2025-02-27 Esfahan University of Medical Sciences Exercise training and type 2 diabetes The effect of aerobic and resistance and combined exercise on the expression of mir-15a, muscular strength and endurance in women with type 2 diabetes. 2025-02-19 anticipated 80 Complete https://irct.ir/trial/79511 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive, Randomization description: Initially, participants are evaluated and ranked according to factors such as muscle strength or endurance and cardiovascular endurance, and subsequently categorized into two groups based on their preferences for specific types of exercise, Blinding description: Participants dose not know of their group assignment. The researcher does not know which group each individual is in. The clinical monitor does not know each participant's group assignment. N/A Type 2 diabetes mellitus. Intervention 1: Control group: Having a normal life routine within 8 weeks. Intervention 2: Intervention group: Performing aerobic exercise. Intervention 3: Intervention group: Performing endurance exercise. Intervention 4: Intervention group: Performing combined exercise. Yes - There is a plan to make this available What will be shared: It can be available upon request from academic researchers, in coordination with the university's Vice President for Research. When: Three months after publication, the article can be made available at the discretion of the corresponding author and the university's vice president for research. To whom: Only academic researchers can access this information. Conditions: The use of data for statistical analysis and inferential statistics is not permitted. Where to obtain: First, coordination must be made with the university's vice president for research and then with the corresponding author. How to obtain: Official request to the Vice President for Research of the university, administrative correspondence from the Vice President for Research to the corresponding author Comments:
public Sahar Ghasemipour
No.19, Shahid Rahimi Alley, Vahdat Ave.
Falavarjan Iran (Islamic Republic of) 8458174338 +98 31 3747 4393 Sghasemipr@spr.ui.ac.ir The University of Isfahan scientific Mozhgan Karimifar
Isfahan University of Medical Sciences, Hezar Jarib Ave.
Isfahan Iran (Islamic Republic of) 1111111111 +98 913 328 0072 mozhgan_karymyfar@yahoo.com Esfahan University of Medical Sciences Iran (Islamic Republic of) Gender: Female Aged between 30-60 years Not participating in regular physical activity Not using drugs Not using insulin injections Normal examination of the diabetic foot Not chest pain or heaviness or history of hospitalization for heart disease Not history of retinal bleeding and Avastin injection( No history of Proliferative retinopathy) No other underlying disease 40 years 60 years Female Voluntary withdrawal of participants from continuing the study Having a specific illness that prevents physical activity Occurrence of physical injury Absence of more than three session in sports interventions Pregnancy E11.9 Type 2 diabetes mellitus without complications Lifestyle Lifestyle Lifestyle Lifestyle Control group: Having a normal life routine within 8 weeks Intervention group: Performing aerobic exercise Intervention group: Performing endurance exercise Intervention group: Performing combined exercise MiRNA-15a, FBS, HDL, LDL, CREATININE, Muscle endurance and strength. Timepoint: 48 hours before intervention, after intervention for 2 months. Method of measurement: Blood sampling, Dynamometer, Fitness tests. Isfahan University of Medical Sciences Approved 2025-02-19 Isfahan University of Medical Sciences - Alzahra Research Centers Complex Floor 13, Block A, Ministry of Health & Medical Education Headquarters, Between Zarafashan & South Falamak, Qods Town Tehran Isfehan Iran (Islamic Republic of)