IRCT20230202057310N16 IRCT 2025-01-22 Muhammad Institute of Medical and Allied Sciences, Multan Curcumin Gel Along With Ultrasound and Eccentric Exercises On Patellar Tendinopathy Management Formulation And Evaluation of Curcumin Gel Along With Ultrasound and Eccentric Exercises On Patellar Tendinopathy Management 2025-01-01 anticipated 90 Complete https://irct.ir/trial/80759 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: The randomization process will be conducted using computer-generated random numbers to assign participants to treatment groups in a predefined allocation sequence. A stratified or block randomization approach will be used to ensure balance between groups for key variables (e.g., age, gender, baseline disease severity). Medications will be prepared and packaged in identical numbered white boxes according to the allocation sequence. Each box will have a unique medication number corresponding to the assigned treatment, ensuring blinding. The allocation sequence and treatment codes will be securely stored and accessible only to the principal investigator, who is not involved in participant interactions or outcome assessments, Blinding description: The statistical analyst and outcome assessor will be blinded to treatment allocation by using securely stored randomization codes, accessible only to an independent party. Data will be analyzed using anonymous identifiers, and group allocation will be revealed only after data collection and analysis are complete. This ensures minimization of bias. 2-3 Patellar Tendinopathy. Intervention 1: Intervention group: Group A: Curcumin-aloe vera gel + ultrasound + eccentric exercises; Ultrasound Application: - Administer therapeutic ultrasound using a frequency of 3 MHz in pulsed mode (intensity of 1–1.5 W/cm²) for 5–10 minutes on the patellar tendon area. Apply curcumin-aloe vera gel before ultrasound therapy to enhance penetration. Treatment frequency: 3 times per week. Focus on slow eccentric loading exercises for the quadriceps, such as decline squats. - Exercise progression: Gradually increase weight/resistance over 8 weeks. - Sessions: 3–4 times per week, supervised by a physiotherapist. Intervention 2: Control group: Group B: Placebo-aloe vera gel + ultrasound + eccentric exercises (Ultrasound Application: - Administer therapeutic ultrasound using a frequency of 3 MHz in pulsed mode (intensity of 1–1.5 W/cm²) for 5–10 minutes on the patellar tendon area. Apply placebo-aloe vera gel before ultrasound therapy to enhance penetration. Treatment frequency: 3 times per week. Focus on slow eccentric loading exercises for the quadriceps, such as decline squats. - Exercise progression: Gradually increase weight/resistance over 8 weeks. - Sessions: 3–4 times per week, supervised by a physiotherapist. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is N/A