IRCT20250124064503N1 IRCT 2025-02-03 Khawaja Muhammad Safdar Medical College/Allama Iqbal Memorial Teaching Hospital, Pakistan To Compare Efficacy and safety of Topical Dapsone 5% versus Topical Clindamycin 1% In Treatment of Mild to Moderate Acne Vulgaris OUTCOME OF TOPICAL DAPSONE 5% VERSUS TOPICAL CLINDAMYCIN 1% IN TREATMENT OF MILD TO MODERATE ACNE VULGARIS 2025-02-03 anticipated 132 Complete https://irct.ir/trial/81647 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: A brief history of demographic information and written informed consent will be taken from each patient. Patients will be examined by dermatologists and will be graded. Patients will be randomly allocated using sealed opaque envelops bearing A= Clindamycin 1% gel group and B= Dapsone 5% gel group. Dapsone gel topically will be applied at bedtime on the lesions daily for 12 weeks. While clindamycin 1% gel treatment will be applied twice daily for 12 weeks. The outcome of both treatments will be assessed in 12 weeks of treatment . 3 Acne Vulgaris. Intervention 1: Intervention group 1: Dapsone 5% Gel. Intervention 2: Intervention group 2: Clindamycin 1%. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is There is no further information