<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20250121064460N1</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2025-03-02</date_registration>
      <primary_sponsor>Tehran University of Medical Sciences</primary_sponsor>
      <public_title>The effect of foam rolling on the hamstring muscle</public_title>
      <acronym></acronym>
      <scientific_title>Effects of Foam Rolling on Hamstring Deep Fascia Stiffness, Pressure Pain Threshold, Flexibility and Active Jumping in Ameutre Athletes following Delayed Onset Muscle Soreness.</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2025-02-28</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>24</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/82080</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: The sampling method in this study will be available sampling. The samples will be randomly assigned to two groups using the Stratified Permuted Block Randomization method with 6 blocks of 4. In this method, A will represent group one (foam rolling group) and B will represent group two (control group). In this way, the order of interventions A and B in the form of blocks from number 1 to 6 will be determined by the project's methodological consultant and provided to the project's executive supervisor, and the researcher will obtain assignments from the executive supervisor to assign each eligible person. The executive supervisor first selects the block using a table of random numbers, and then the eligible people are assigned to one of the two groups A or B based on the order previously determined in the table, Blinding description: The outcome assessor will be blinded to the treatment groups.</study_design>
      <phase>N/A</phase>
      <hc_freetext>Delayed Onset Muscle Soreness.</hc_freetext>
      <i_freetext>Intervention 1: Intervention group: First, the variables are assessed and then the participants will perform the desired eccentric exercises. Based on the protocol mentioned in the Mendiguchia et al (2020) study, Nordic hamstring exercise involves eccentric contractions and will cause muscle pain. Nordic exercise consists of 5 sets of 8 repetitions, with 10 seconds of rest between repetitions and 2 to 3 seconds of rest between sets. After performing Nordic exercises, they used a foam roller. In this way, they put their maximum body weight on the foam roller and slid their body mass along it, starting from the proximal part of the back area at the hamstring muscle, then moving down and gradually moving them towards the knee, and when the foam rolling reached the distal thigh area, they returned it to the initial position. These steps were performed at a rotation speed of 30 revolutions per minute and foam rolling was performed in 4 sets of 45 seconds, with a 15-second rest between sets. In the second and third sessions, which will be 24 and 48 hours after the initial Nordic exercises, the foam rolling steps will be repeated. In order to follow up on the effect 72 hours after the Nordic exercises, a final evaluation of the variables will be performed. The evaluation and performance of the ultrasound test with shear wave was performed in collaboration with a radiologist, and the results of the evaluation before, after the first session, and 72 hours after the exercises will be recorded. The evaluation of the pressure pain and jump length variables will be performed by the first researcher in an environment close to the ultrasound location. Intervention 2: Control group: First, the variables will be evaluated and then the participants will perform the desired eccentric exercises. Based on the protocol mentioned in the Mendiguchia et al (2020) study, the Nordic hamstring exercise will include eccentric contractions and will cause muscle pain. The Nordic exercise will consist of 5 sets of 8 repetitions, with 10 seconds of rest between repetitions and 2 to 3 seconds of rest between sets. In the first session, the control group will not receive treatment after performing the exercises. In order to follow up on the effect 72 hours after performing the Nordic exercises, a final evaluation of the variables will be performed. The evaluation and performance of the ultrasound test with shear wave will be performed in collaboration with a radiologist and the results of the evaluation before, after the first session and 72 hours after the exercises will be recorded. The evaluation of the pressure pain variables and jump length will be performed by the first researcher in an environment close to the ultrasound location.</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>Undecided - It is not yet known if there will be a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for indecision in sharing IPD is No more information available.</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Negin Nateghi</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Tehran - Enghelab St. - Pich Shemiran - Faculty of Rehabilitation, Tehran University of Medical Sciences</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1148965111</zip>
        <telephone>+98 21 7753 3939</telephone>
        <email>nateqinegin@gmail.com</email>
        <affiliation>Tehran University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Siamak Bashardoust Tajali</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Tehran - Enghelab Street - Shemiran Corner - Faculty of Rehabilitation, Tehran University of Medical Sciences</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1148965111</zip>
        <telephone>+98 21 7753 3939</telephone>
        <email>s_bashardoust@sina.tums.ac.ir</email>
        <affiliation>Tehran University of Medical Sciences</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Having a normal BMI
Age range between 18-35 years
All participants must be of the same sex and there should be no statistically significant difference between the groups in terms of gender
Amateur athlete (between 1 and 4 hours of exercise per week).
Absence of central and peripheral neurological disorders.
Absence of skin conditions in the hamstring muscle area.
Absence of joint injuries (capsular, ligamentous, etc.).
Absence of immunological diseases or malignancy.</inclusion_criteria>
      <agemin>18 years</agemin>
      <agemax>35 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Participant withdrawal from cooperation.
Participant feeling dissatisfied.
Participant intolerance to research procedures.
Taking anticoagulant medication.
Having vascular disease and diabetes.</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M62.9</hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Disorder of muscle, unspecified</hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
      <i_code>Other</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention group: First, the variables are assessed and then the participants will perform the desired eccentric exercises. Based on the protocol mentioned in the Mendiguchia et al (2020) study, Nordic hamstring exercise involves eccentric contractions and will cause muscle pain. Nordic exercise consists of 5 sets of 8 repetitions, with 10 seconds of rest between repetitions and 2 to 3 seconds of rest between sets. After performing Nordic exercises, they used a foam roller. In this way, they put their maximum body weight on the foam roller and slid their body mass along it, starting from the proximal part of the back area at the hamstring muscle, then moving down and gradually moving them towards the knee, and when the foam rolling reached the distal thigh area, they returned it to the initial position. These steps were performed at a rotation speed of 30 revolutions per minute and foam rolling was performed in 4 sets of 45 seconds, with a 15-second rest between sets. In the second and third sessions, which will be 24 and 48 hours after the initial Nordic exercises, the foam rolling steps will be repeated. In order to follow up on the effect 72 hours after the Nordic exercises, a final evaluation of the variables will be performed. The evaluation and performance of the ultrasound test with shear wave was performed in collaboration with a radiologist, and the results of the evaluation before, after the first session, and 72 hours after the exercises will be recorded. The evaluation of the pressure pain and jump length variables will be performed by the first researcher in an environment close to the ultrasound location.</i_keyword>
      <i_keyword>Control group: First, the variables will be evaluated and then the participants will perform the desired eccentric exercises. Based on the protocol mentioned in the Mendiguchia et al (2020) study, the Nordic hamstring exercise will include eccentric contractions and will cause muscle pain. The Nordic exercise will consist of 5 sets of 8 repetitions, with 10 seconds of rest between repetitions and 2 to 3 seconds of rest between sets. In the first session, the control group will not receive treatment after performing the exercises. In order to follow up on the effect 72 hours after performing the Nordic exercises, a final evaluation of the variables will be performed. The evaluation and performance of the ultrasound test with shear wave will be performed in collaboration with a radiologist and the results of the evaluation before, after the first session and 72 hours after the exercises will be recorded. The evaluation of the pressure pain variables and jump length will be performed by the first researcher in an environment close to the ultrasound location.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Deep Fascia Stiffness. Timepoint: Before the intervention, before, 24 hours after, and 72 hours after the intervention. Method of measurement: Shear Wave Elastography (SWE) Results.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Pressure Pain Threshold. Timepoint: Before the intervention, before, 24 hours after, and 72 hours after the intervention. Method of measurement: Algometer.</sec_outcome>
      <sec_outcome>Flexibility. Timepoint: Before the intervention, before, 24 hours after, and 72 hours after the intervention. Method of measurement: Goniometer.</sec_outcome>
      <sec_outcome>Active Jumping. Timepoint: Before the intervention, before, 24 hours after, and 72 hours after the intervention. Method of measurement: Vertical jump test.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Tehran University of Medical Sciences</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2025-01-08</approval_date>
        <contact_name>Research Ethics Committees of School of Nursing and Midwifery &amp; Rehabilitation - Tehran University o</contact_name>
        <contact_address>School of Rehabilitation of Tehran University of MedicalSciences, Piche Shemiran, Enghelab Ave, Tehran, Iran Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
