Investigating the effect of iron supplementation with and without vitamin c on iron deficiency anemia, iron and hematologic Indices of patients reffered to touba clinic
Determining the effect of iron supplementation with and without vitamin C on iron deficiency anemia, iron and hematological indices in patients with iron deficiency anemia
Design
Randomized Trial without blind assessment
Settings and conduct
Randomized Trial without blind assessment on anemic patients reffering ro razi hospital and touba clinic of Mazandaran University of Medical Science in 2025
Participants/Inclusion and exclusion criteria
Iron deficiency anemia and willingness to participate in the study and follow-up
Taking iron or blood supplements within the past two months, acute infection, severe liver failure, gastrointestinal bleeding, taking multivitamins or supplements containing vitamin C within the past two months
Intervention groups
Control: Ferrous Glycine Sulphate: 80 mg for t months
Intervention: Ferrous Glycine Sulphate: 80 mg plus vitamin c 250 mg daily for 2 months
Main outcome variables
Hb, Ferritin, Fe
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20241127063874N1
Registration date:2025-06-27, 1404/04/06
Registration timing:registered_while_recruiting
Last update:2025-06-27, 1404/04/06
Update count:0
Registration date
2025-06-27, 1404/04/06
Registrant information
Name
Zohreh Ehsani
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 911 177 0256
Email address
zehsani@mazums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2025-06-22, 1404/04/01
Expected recruitment end date
2025-11-21, 1404/08/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Investigating the effect of iron supplementation with and without vitamin c on iron deficiency anemia, iron and hematologic Indices of patients reffered to touba clinic
Public title
Vitamin c in anemia
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Iron deficiency anemia and willingness to participate in the study and follow-up
Exclusion criteria:
Receiving iron or blood supplements within the past two months, acute infection, severe liver failure, gastrointestinal bleeding, taking multivitamins or vitamin C supplements within the past two months
Age
From 18 years old to 65 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
60
Randomization (investigator's opinion)
N/A
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of Mazandaran University of Medical Science
Street address
Moallem square
City
Sari
Province
Mazandaran
Postal code
۴۸۱۵۷۳۳۹۷۱
Approval date
2024-01-09, 1402/10/19
Ethics committee reference number
IR.MAZUMS.REC.1402.591
Health conditions studied
1
Description of health condition studied
Anemia
ICD-10 code
D50
ICD-10 code description
Iron deficiency anemia
Primary outcomes
1
Description
Changes in Hb anf Ferritin and Fe
Timepoint
2 months after intervention
Method of measurement
Biochemical and ELISA methods
Secondary outcomes
empty
Intervention groups
1
Description
During this study, Ferrofort Duodenal tablets produced by the pharmaceutical company (Abidi, Ferrous Glycine Sulphate: 80 mg) will be prescribed to patients in two intervention groups. The dosage of the tablets in both groups is one tablet daily. This intervention will be carried out for two months.
Category
Treatment - Drugs
2
Description
In Vitamin C group in addition to daily Ferrous Glycine Sulphate: 80 mg, eurovital vitamin C 250 mg tablet is added to treatment. Once daily for two months.