IRCT20251013067605N1 IRCT 2025-10-19 Mashhad University of Medical Sciences Effect of Dexmedetomidine on Acute Renal Injury Patients undergoing CABG Studying the effect of intraoperative dexmedetomidine infusion on acute renal failure in diabetic patients undergoing CABG surgery 2025-11-24 anticipated 60 Complete https://irct.ir/trial/86781 interventional Randomization: Not randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention, Blinding description: Despite of giving informed consent, participants are unaware of whether they are receiving the drug or placebo. Similarly, the outcome assessor only sees and notes the outcomes and he is unaware of whether the patient received the drug or placebo. 3 Patients with diabetes treated with pills. Intervention 1: Intervention group: Dexmedetomidine (Medonex) diluted in saline at a concentration of 0.5 micrograms/kg/hour) In the placebo group, normal saline solution was administered via an infusion pump at the same rate and continued until the end of the surgery. Intervention 2: Control group: In the placebo group,0.9% normal saline solution was administered by infusion pump at a rate of 0.5 micrograms/kg/hour, starting at the beginning of surgery and continuing until the end of surgery. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is I have not decided yet, but if the data is requested by email to the corresponding author, the data will be made available to other researchers.