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IRCT20260810070604N1 IRCT 2026-08-20 Riphah International University Faisalabad Integrated Pain Neuroscience Education and Motor Control Training Versus McKenzie Therapy in the Treatment of Lumbar Radiculopathy RCT Bio Psychomotor Rehabilitation Integrating Pain Neuroscience Education and Motor Control Training Versus McKenzie Therapy in Lumbar Radiculopathy 2026-09-01 anticipated 36 Recruiting https://irct.ir/trial/92612 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Parallel-group, single-blinded RCT with two active intervention groups, randomly allocated in a 1:1 ratio. Both groups will receive active physiotherapy interventions, with participants blinded to group allocation, Randomization description: Participants are randomly allocated individually into two groups (18 participants each) using computer-generated simple randomization. Group A receives PNE with Motor Control Training, while Group B receives McKenzie Theray. Allocation concealment is maintained using sequentially numbered, opaque, sealed envelopes opened after baseline assessment, Blinding description: This is a single-blinded randomized clinical trial with two active intervention groups. Only the participants will be blinded to their group allocation and the study hypothesis. Both groups will receive physiotherapy interventions, with Group A receiving Motor Control Training with Pain Neuroscience Education and Group B receiving McKenzie Therapy. The physiotherapists and outcome assessor will not be blinded. N/A Lumbar radiculopathy is a clinical condition caused by irritation, inflammation or compression of a nerve root in the lumbar spine. it commonly presents with low back pain radiation into buttock and lower extremity, along with symptoms such as numbness, tingling or muscle weakness. Disc herniation and degenerative changes of the lumbar spine are common causes.. Intervention 1: Intervention group 1: Group A will receive Pain Neuroscience Education and Motor Control Training (PNE+MCT). Patients will receive PNE and MCT for 2 weeks with five 30 to 40 minute session per week. PNE will be given for 10-15 minutes at the beginning of each session in order to lessen fear-avoidance beliefs and explain neurophysiology of pain. MCT, which concentrated on the activation as well as coordination of deep trunk muscle groups, like the transverse abdominus and multifidus will came next. Exercises will range from basic activation (breathing, drawing in the abdomen) to muscle control (heel slides. knee bent fallout) and functional exercises (bridging, bird-dog, sit-stand) within a pain-free range. Intervention 2: Intervention group 2: Group B will receive McKenzie Therapy for 2 weeks, with five sessions each week lasting 20 to 30 minutes each. Lumbar extension exercises, such as prone lying down, prone on elbows and prone press-ups will be the main emphasis of the intervention repeated motions and prolonged positions determined by directional preferance. McKenzie exercises will be performed for 10 repetitions per exercise, for 3 sets per session. No - There is not a plan to make this available Justification or reason for not sharing IPD is The deidentified individual participant data will not be made publicly available due to participant privacy and confidentiality considerations. Data will be retained securely by the research team and used only for the purposes specified in the approved research protocol.
public Dr. Lyba Musaddiq
Riphah International University Faisalabad Campus
Faisalabad Pakistan 38090 +92 322 6380789 lyba.musaddiq@riphahfsd.edu.pk Riphah International University Faisalabad scientific Sehar Naz
Riphah International University Faisalabad, Main Satiana Road, adjacent to Fish Farm in Faisalabad, Pakistan
Faisalabad Pakistan 38090 +92 325 0677170 seharnaz70rb@gmail.com Riphah International University Faisalabad Pakistan Pakistan Pakistan Pakistan Age between 28-50 years Clinically diagnosed patients with lumbar radiculopathy Both males and females were included Participants who had a confirmed disc herniation between L4-S1 levels through MRI Had pain for at least 3 months Had positive SLR between 40 and 70 degrees 28 years 50 years Both Fracture Trauma Inflammatory disorder Lumbar instability Scoliosis Patients with RA and other systemic diseases M47.816 Spondylosis without myelopathy or radiculopathy, lumbar region Rehabilitation Rehabilitation Intervention group 1: Group A will receive Pain Neuroscience Education and Motor Control Training (PNE+MCT). Patients will receive PNE and MCT for 2 weeks with five 30 to 40 minute session per week. PNE will be given for 10-15 minutes at the beginning of each session in order to lessen fear-avoidance beliefs and explain neurophysiology of pain. MCT, which concentrated on the activation as well as coordination of deep trunk muscle groups, like the transverse abdominus and multifidus will came next. Exercises will range from basic activation (breathing, drawing in the abdomen) to muscle control (heel slides. knee bent fallout) and functional exercises (bridging, bird-dog, sit-stand) within a pain-free range. Intervention group 2: Group B will receive McKenzie Therapy for 2 weeks, with five sessions each week lasting 20 to 30 minutes each. Lumbar extension exercises, such as prone lying down, prone on elbows and prone press-ups will be the main emphasis of the intervention repeated motions and prolonged positions determined by directional preferance. McKenzie exercises will be performed for 10 repetitions per exercise, for 3 sets per session. Intensity of pain experienced by patients with lumbar radiculopathy. Timepoint: At baseline before intervention and immediately after completion of 10 treatment sessions over 2 weeks. Method of measurement: Numeric Pain Rating Scale to measure pain intensity. NPRS is a 11-point, unidimensional tool (0-10) where o indicates no pain, 1-3 indicates mild pain, 4-6 indicates moderate pain and 7-10 indicates severe pain. Level of disability and functional limitation associated with lumbar radiculopathy. Timepoint: At baseline before intervention and immediately after completion of 10 treatment sessions over 2 weeks. Method of measurement: Roland Morris Disability Questionnaire (RMDQ) to measure level of disability and functional limitations where 0 indicates no disability, 1-8 indicates mild disability, 9-16 indicates moderate disability and 17-24 indicates severe disability. Fear of movement and hesitation associated with pain in patients with lumbar radiculopathy. Timepoint: At baseline before intervention and immediately after completion of 10 treatment sessions over 2 weeks. Method of measurement: Tampa Scale of Kinesiophobia to measure fear of movement and hesitation of movement. The TSK score ranges from 17-68, with lower scores indicating less fear of movement and higher scores indicating greater fear of movement. Pain distribution and location of pain in patients with lumbar radiculopathy. Timepoint: At baseline before intervention and immediately after completion of 10 treatment sessions over 2 weeks. Method of measurement: Michigan Body Map for distribution and location of pain and musculoskeletal symptoms across different body regions. The MBM assesses 35 body regions, with each symptomatic region receiving a score of 1 and each non-symptomation region receiving a score of 0. The total score ranges from 0-35 where a lower score indicating fewer symptomatic body regions while a higher score indicates symptoms in more body regions. Academic Research Approved 2026-06-04 Research and Ethics Committee (REC) Riphah International University Faisalabad Campus, Main Satayana Road (Adjacent to Fish Farm), Faisalabad, Pakistan Faisalabad Punjab Pakistan