IRCT20260824070775N1 IRCT 2026-09-02 Pak Emirates Military Hospital Rawalpindi Comparison of Efficacy of Intranasal versus Intravenous Dexmedetomidine for Procedural Sedation in Pediatric Patients Undergoing Magnetic Resonance Imaging Comparison of Efficacy of Intranasal versus Intravenous Dexmedetomidine for Procedural Sedation in Pediatric Patients Undergoing Magnetic Resonance Imaging 2026-11-01 anticipated 126 Pending https://irct.ir/trial/92808 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Other, Purpose: Supportive. 0 (exploratory trials) Procedural Sedation. Procedural anxiety. Intervention 1: Intranasal dexmedetomidine group: Dexmedetomidine at a dose of 2–3 µg/kg will be administered as nasal drops divided equally between both nostrils approximately 30–45 minutes before imaging. The child will be kept in a supine position for 1–2 minutes to optimize mucosal absorption, and the dose may be repeated up to a maximum of 200 µg if necessary. Intervention 2: Intravenous dexmedetomidine group: Venous access will be secured by phlebotomist (more than 5 years of experience) and dexmedetomidine will be administered as a loading dose of 0.5–2 µg/kg over 10 minutes, followed by a maintenance infusion of 0.5–1.5 µg/kg/hour, adjusted according to the required level of sedation. No - There is not a plan to make this available Justification or reason for not sharing IPD is Individual participant data will not be shared outside the primary research team due to institutional policy and patient privacy restrictions governing pediatric medical records. Aggregate results will be made fully available through publication