Protocol summary

Summary
The overall objective of the project: determining the amino acid glutamine supplementation on indices of muscle damage after eccentric resistance exercise in untrained men. Methods: this study is experimental subjects young male student volunteers normal weight (BMI between 19 and 25) University of Applied Sciences are Persepolis sport activities, dietary supplements, not drugs and painkillers and diet plans follow a specific pattern. In the case of the 7 days before the test, each of the above criteria are not respected subjects excluded from the study. A week before the test and after completing health questionnaires and consent form, the subject during a meeting with the means and methods of measure are introduced. At the same session, making Weight and height which, as the record of the meeting and recorded in knee extension subject to. Prior to the training program to measure fasting subjects index case (the enzyme creatine kinase ) cc 5 of venous blood from the forearm to get , motion range as measured by a goniometer and also muscle pain perception index by 6 -point scale (PAS) Shylaja (2003 ) will be evaluated, subjects drank his drink for 30 minutes after eating , then start doing the exercise protocol to damage to the muscle . Supplement for 1 / 0 g glutamine per kg of body weight (Karen pharmaceutical company ) was combined with 300 ml of water and placebo groups Maltv dextrin ( Karen pharmaceutical company ) the amount of water used to be ¬ . Delayed Onset Muscle Soreness (DOMS) and muscle damage in the muscles of the lower body with the knee extended, with about 70% 1RM weights similar research project LarocheDain (2005) be cause [6] . 24 and 48 hours after eccentric activity, an index of blood (CK), plus perceptions of muscle pain and range of motion should be evaluated again making .

General information

Acronym
IRCT registration information
IRCT registration number: IRCT2014040810826N7
Registration date: 2014-07-26, 1393/05/04
Registration timing: retrospective

Last update:
Update count: 0
Registration date
2014-07-26, 1393/05/04
Registrant information
Name
Azadeh Nadjarzadeh
Name of organization / entity
Shahid Sadoughi University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 912 202 2817
Email address
azadnajarzadeh@ssu.ac.ir
Recruitment status
Recruitment complete
Funding source
Individual & National Olympic Academy
Expected recruitment start date
2014-02-20, 1392/12/01
Expected recruitment end date
2014-04-21, 1393/02/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of Glutamine supplementation on muscle damage markers after Eccentric resistance exercise in untrained men
Public title
The effect of Glutamine supplementation on muscle damage markers
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria: men; non athletes; non-smokers with normal BMI and age between 20 to 30 years old. Exclusion criteria: being athlete; smoking; an abnormal BMI (under weight - overweight and obesity) and non-compliance with conditions such as changes in diet during the study; taking drug or certain supplements and age less than 20 years over 30 years old.
Age
From 20 years old to 30 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 80
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Shahid Sadooghi University of Medical Sciences
Street address
Shahid Sadooghi University of Medical Sciences, Imam Hossein Square
City
Yazd
Postal code
8944157963
Approval date
2014-02-08, 1392/11/19
Ethics committee reference number
223114/17/پ

Health conditions studied

1

Description of health condition studied
Muscle damage
ICD-10 code
M-63
ICD-10 code description
Disorders of muscle in diseases classified elsewhere

Primary outcomes

1

Description
Serum creatine kinase enzyme
Timepoint
Zero, 24 and 48 hours after intervention
Method of measurement
Level of enzyme activity by photometric method.

2

Description
Muscle pain perception
Timepoint
Zero, 24 and 48 hours after intervention
Method of measurement
Pain is measured using a scale numbered graphics PAS

3

Description
Range of motion
Timepoint
Zero, 24 and 48 hours after intervention
Method of measurement
Goniometer Lafayette

Secondary outcomes

empty

Intervention groups

1

Description
0.1 grams of glutamine per kg of body weight (Karen pharmaceutical company) was combined with 300 ml of water
Category
Prevention

2

Description
Maltodextrin Placebo group of 0.1 grams per kilogram of body weight, which is combined with 300 ml of water.
Category
Placebo

Recruitment centers

1

Recruitment center
Name of recruitment center
Academic University - Applied Club
Full name of responsible person
Dr. Vajihollah Cheshmesari
Street address
Tehran Highway, 25th st., Azadegan Boulevard, Kurdistan
City
Tehran

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
National Olympic Academy
Full name of responsible person
Dr. Mohammad Reza Sharif
Street address
Enghelab Sports Complex, Seul st.
City
Tehran
Grant name
ندارد
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
National Olympic Academy
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Shahid Sadooghi University of Medical Sciences
Full name of responsible person
Hadi Atarod
Position
Student of Medicine
Other areas of specialty/work
Street address
International Campus of Shahid Sadooghi University of Medical Sciences, 5th kilometer Exclusive Bafgh
City
Yazd
Postal code
8944157963
Phone
+98 35188014557
Fax
+98 35 1836 7636
Email
atarodsportnutrition@gmail.com; hadi_atarod@yahoo.com
Web page address
www.ssu.ac.ir/ib

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shahid Sadooghi University of Medical Sciences
Full name of responsible person
Dr. Azadeh Najarzadeh
Position
Assistant professor
Other areas of specialty/work
Street address
Shahid Sadooghi University of Medical Sciences, Imam Hossein Square
City
Yazd
Postal code
8944157963
Phone
+98 35 1624 0691
Fax
+98 35 1836 7636
Email
azadnajarzadeh@ssu.ac.ir; azmm1383@yahoo.com
Web page address
www.ssu.ac.ir/ib

Person responsible for updating data

Contact
Name of organization / entity
Shahid Sadooghi University of Medical Sciences
Full name of responsible person
Hadi Atarod
Position
Student of Medicine
Other areas of specialty/work
Street address
Shahid Sadooghi University of Medical Sciences, Imam Hossein Square
City
Yazd
Postal code
8944157963
Phone
+98 21 2621 6193
Fax
+98 35 1836 7636
Email
atarodsportnutrition@gmail.com
Web page address
www.ssu.ac.ir/ib

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
Loading...