Effect of dry needling on neuromuscular junction response and sympathetic skin response in patients with upper trapeizus myofascial trigger points compared with healthty subjects
Introduction: Dry needling (DN) is an effective method for the treatment of myofascial trigger points (MTrPs). The aim of the present study will be to assess the immediate neurophysiological efficacy of dry needling in patients with upper trapezius MTrPs.
Methods and analysis: A prospective, controlled clinical trial is designed to include patients with upper trapezius MTrPs and volunteered healthy subjects to receive one session DN. The primary outcome measures are neuromuscular junction response (NMJR) and sympathetic skin response (SSR). The secondary outcomes are the pain intensity and the pressure pain threshold. Data will be collected at baseline and immediately after intervention.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2013031612828N1
Registration date:2013-04-04, 1392/01/15
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2013-04-04, 1392/01/15
Registrant information
Name
Maryam Abbaszadeh-Amirdehi
Name of organization / entity
Tehran University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 2222 1577
Email address
abbaszadeh_m@razi.tums.ac.ir
Recruitment status
Recruitment complete
Funding source
Tehran University of Medical Sciences
Expected recruitment start date
2013-04-04, 1392/01/15
Expected recruitment end date
2013-06-04, 1392/03/14
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of dry needling on neuromuscular junction response and sympathetic skin response in patients with upper trapeizus myofascial trigger points compared with healthty subjects
Public title
The neurophysiological effects of dry needling in patients with upper trapeizus myofascial trigger points
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: subjects with aged between 20 and 40 year old; upper trapezius active Myofascial trigger points (MTrPs).
Exclusion criteria: subjects less than 20 years and more than 40 years; subjects with a history of other shoulder or spinal disorders; neck and upper extremity surgery; acute disease; muscle diseases; neurological or systemic disorder (such as lupus erythematus, scleroderma); epilepsy; pregnancy; using sedative drugs; needle phobia; bleeding disorder; anticoagulant medication; previous experience with dry needling for myofascial pain; Skin lesion and infection or inflammatory oedema at MTrPs.
Age
From 20 years old to 40 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
30
Randomization (investigator's opinion)
Not randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features
This study is a controlled clinical trial designed to investigate the effectiveness of dry needling on neuromuscular junction response and sympathetic outflow in patients with upper trapeizus MTrPs compared with healthy individual matched group.
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Tehran University of Medical Sciences
Street address
Tehran University of Medical Sciences, Enghelab Ave., Tehran, Iran
City
Tehran
Postal code
1417614411
Approval date
2012-09-17, 1391/06/27
Ethics committee reference number
2185
Health conditions studied
1
Description of health condition studied
myofascial trigger point
ICD-10 code
M00-M99
ICD-10 code description
Diseases of the musculoskeletal system and connective tissue
Primary outcomes
1
Description
Neuromuscular Junction Response (NMJR)
Timepoint
before intervention and immediately after intervention
Method of measurement
Electrodignostic technique of repeatitive nerve stimulation (RNS) in trapezius muscle
2
Description
Sympathetic Skin Response (SSR)
Timepoint
before intervention and immediately after intervention
Method of measurement
stimulus over the median nerve at the wrist and records on the palm of the hand
Secondary outcomes
1
Description
Pain Intensity
Timepoint
before intervention and immediately after intervention
Method of measurement
Pain intensity will be self rated by subjects on a 0-10 numerical rating scale with 0 representing no pain and 10 representing the worst imaginable pain
2
Description
Pressure Pain Threshold
Timepoint
before intervention and immediately after intervention
Method of measurement
; by use a pressure algometer According to Kilogram per square centimeter
Intervention groups
1
Description
The sterile acupuncture needles of 0.30 mm diameter and 50 mm long will be used for both groups. The needle will be inserted into the skin over the palpated trigger point and will be advanced until it reaches the trigger point. Each trigger point will be repeatedly needled for 1 – 2 minutes.
Category
Treatment - Other
2
Description
The sterile acupuncture needles of 0.30 mm diameter and 50 mm long will be used. The needle will be inserted into the skin over the Trigger Point equivalent of upper terapezius in healthy subjects. Each point will be repeatedly needled for 1 – 2 minutes.
Category
Treatment - Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Electrophysiology center of School of Rehabilitation, Tehran University of Medical Sciences
Full name of responsible person
Maryam Abbaszadeh-Amirdehi
Street address
School of Rehabilitation of Tehran University of Medical Sciences, Mirdamad Blv, Shahnazari St, Nezam St, Tehran, Iran
City
Tehran
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Dr. Mansouri
Street address
Tehran University of Medical Sciences, Enghelab Ave., Tehran, Iran
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tehran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Tehran University of Medical Sciences
Full name of responsible person
Maryam Abbaszadeh-Amirdehi
Position
PhD candidate of physiotherapy
Other areas of specialty/work
Street address
School of Rehabilitation of Tehran University of Medical Sciences, Mirdamad Blv, Shahnazari St, Nezam St, Tehran, Iran