This study aims to compare the effectiveness of Epley maneuver and Cinnarizine in treatment of BPPV.
In this randomized clinical trial patients with Benign Positional Paroxysmal Vertigo (BPPV) attending to vertigo clinic of Baqiyatallah hospital, Tehran, Iran in 2015 and 2016 will be assessed for eligibility. All patients will be informed of study process and possible side effects. A written informed consent will be obtained from all patients. Patients with definite diagnosis of BPPV, up to 2 days after diagnosis, and those who have not received any treatments for BPPV will be included. BPPV diagnosis will be made by single physician based on history taking and hallpike test. Patients with no definite diagnosis and those suspicious for other causes of vertigo, especially CNS involvement, will be excluded from the study. After being matched regarding age and gender, patients will be randomized to two groups: the first group (A) will undergo Epley repositioning maneuver by single physician and the second group (B) will use Cinnarizine (25mg every 8 hours) for two weeks. The block randomization will be accomplished by the clinic’s automatic turn system and patients were randomized into 2 groups at a ratio of 1:1 and a block size of 4.
In the first visit, results of hallpike test will be recorded for both groups and after first Epley maneuver, group A patients will be recommended to place their head 45 degrees upper the body level during sleep for two days. The patients will be evaluated for symptoms using visual analogue scale (VAS) scoring system before intervention, first and second weeks after intervention. In the second and third visit, Epley maneuver was repeated in group A patients and the results of hallpike test was recorded for both groups.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2016101717413N19
Registration date:2016-10-28, 1395/08/07
Registration timing:retrospective
Last update:
Update count:0
Registration date
2016-10-28, 1395/08/07
Registrant information
Name
Hamidreza Karimi-Sari
Name of organization / entity
Student Research Committee, Baqiyatallah University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 8126 4354
Email address
hrkarimisari@bmsu.ac.ir
Recruitment status
Recruitment complete
Funding source
Deputy of research of Baqiyatallah University of Medical Sciences
Expected recruitment start date
2015-06-22, 1394/04/01
Expected recruitment end date
2016-06-21, 1395/04/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of Epley Maneuver and Cinnarizine in Treatment of Benign Positional Paroxysmal Vertigo
Public title
Comparison of Epley Maneuver and Cinnarizine in Treatment of Benign Positional Paroxysmal Vertigo
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
1- Patients with definite diagnosis of BPPV
2- only up to 2 days after diagnosis
3- those who have not received any treatments for BPPV
Exclusion criteria:
1- Patients with no definite diagnosis
2- those suspicious for other causes of vertigo, especially CNS involvement
3- not willing to participate
4- previous history of treatment
The first group will undergo treatment with Epley Maneuver in the first visit and two more times in first and second weeks after intervention (three times in general)
Category
Treatment - Other
2
Description
The second group will undergo treatment with cinnarizine tablet (25 mg every 8 hours) for two weeks.