Comparison of anesthetic efficacy of 4% articaine and 2% Lidocaine for maxillary Buccal infiltration in patients with irreversible pulpitis. a randomized double- blined clinical trial
This study was to compare the success rate of using two local anesthesia solutions for endodontic treatment of first maxillary molars with irreversible pulpitis. In a randomized double-blinded clinical Trial, fifty patients were randomly assigned to 2 groups of 25 patients each. The exclusion criteria are the presence of systemic disorders; a sensitivity to articaine and lidocaine, and the inclusion criteria included healthy patients having a first maxillary molar teeth with irreversible pulpitis and normal periapical radiographic appearance. Group I patients received a buccal infiltration with 1.8 mL of 2% lidocaine with 1:80000 epinephrine. Group II patients received 1.8 mL of 4% articaine with 1:100000 epinephrine as a buccal infiltration.A visual analogue scale was used to rate pain before anesthesia and discomfort experienced before and during access cavity preparation. Data were analyzed by Tow way repeated measure ANOVA and chi square tests.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT201204302016N5
Registration date:2013-11-23, 1392/09/02
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2013-11-23, 1392/09/02
Registrant information
Name
Masoud Parirokh
Name of organization / entity
Kerman University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 34 1245 7931
Email address
m_parirokh@kmu.ac.ir
Recruitment status
Recruitment complete
Funding source
Vce chancellor for research, Kerman University of Medical Sciences
Expected recruitment start date
2013-11-22, 1392/09/01
Expected recruitment end date
2014-03-16, 1392/12/25
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of anesthetic efficacy of 4% articaine and 2% Lidocaine for maxillary Buccal infiltration in patients with irreversible pulpitis. a randomized double- blined clinical trial
Public title
Comparison of anesthetic efficacy of 4% articaine and 2% Lidocaine for maxillary Buccal infiltration in patients with irreversible pulpitis. a randomized double- blined clinical trial
Purpose
Treatment
Inclusion/Exclusion criteria
The exclusion criteria were the presence of systemic disorders; a sensitivity to articaine 4%with 1:100000 epinephrine and lidocaine2% with 1:80,000 epinephrine; the presence of widening of the periodontal ligament space; the presence of a periapical radiolucency; lactation; pregnancy. Inclusion criteria included healthy patients having a first maxillary molar tooth with irreversible pulpitis and normal periapical radiographic appearance, whit out spontaneously pain that to be needed emergency treatment.
Age
From 18 years old to 80 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
50
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Kerman University of Medical Sciences
Street address
Somaye cross road, Vice chancellor for research building; Kerman University of Medical Sciences
City
Kerman
Postal code
Approval date
2013-05-06, 1392/02/16
Ethics committee reference number
ka/92/114
Health conditions studied
1
Description of health condition studied
irreversible pulpitis
ICD-10 code
ICD-10 code description
Primary outcomes
1
Description
Pain degree
Timepoint
Befor and after intervention
Method of measurement
Visual Analogous Scale(VAS)
Secondary outcomes
empty
Intervention groups
1
Description
Buccal infiltration injection of one cartrige(1.8 ml) articaine 4%
Category
Treatment - Drugs
2
Description
Buccal infiltration injection of one cartrige(1.8 ml) lidocaine 2%
Category
Treatment - Drugs
Recruitment centers
1
Recruitment center
Name of recruitment center
Kerman University of Medical Sciences, School of Dentistry
Full name of responsible person
Hamid Reza Hosseini
Street address
Jomhori Eslami Bloubvared, Shafa str, Dental School of kerman University of Medical Sciences
City
Kerman
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Vice chancellor for research; Kerman University of Medical Sciences
Full name of responsible person
Reza Malekpour Afshar
Street address
Vice chancellor for research, Kerman University of Medical Sciences, Somaye cross road
City
Kerman
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice chancellor for research; Kerman University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Kerman University of Medical Sciences
Full name of responsible person
Hamid Rreza Hosseini
Position
Resident of endodontics
Other areas of specialty/work
Street address
Jomhori Eslami Bloubvared, Headquarter Builidng, Kerman University of Medical Sciences
City
Kerman
Postal code
Phone
+98 34 1247 7841
Fax
Email
hamid_h1979@yahoo.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Kerman University of Medical Sciences
Full name of responsible person
Masoud Parirokh
Position
Professor
Other areas of specialty/work
Street address
Jomhori Eslami Bloubvared, Headquarter Builidng of Kerman University of Medical Sciences
City
Kerman
Postal code
Phone
+98 34 1245 7931
Fax
+98 34 1211 8073
Email
masoudparirokh@gmail.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Kerman University of Medical Sciences
Full name of responsible person
Hamid Reza Hosseini
Position
Resident of endodontics
Other areas of specialty/work
Street address
Jomhori Eslami Bloubvared, Headquarter Builidng of Kerman University of Medical Sciences
City
Kerman
Postal code
Phone
+98 34 1247 7841
Fax
Email
hamid_h1979@yahoo.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)