The aim of the present study was to investigate the effect of 12 weeks of aerobic exercise training on sex hormones and blood markers of airway inflammation in mid-luteal phase of asthmatics women. 24 women with mild to moderate asthma and regular menstrual cycles were selected and divided into two groups including experimental (n=13) and control (n=11) groups. The experimental group performed aerobic exercise training, and the control group remained inactive. The exercise program lasted for 12 weeks, three sessions a week. Each training session consisted of 15 minutes warm up, 30-minute walk on the treadmill with 60-80% of patients’ maximum heart rate and 15 minutes of breathing exercises and cool-down. To reduce problems such as exercise- induced asthma during exercise, American college sport medicine guidelines were used. Before and 24 hours after the last training session, body mass index, VO2peak and blood inflammatory markers such as immunoglobulin E, Eosinophil%, IL-4, IL-5 and IL-13 and also spirometry were measured
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2016052328028N1
Registration date:2017-01-05, 1395/10/16
Registration timing:retrospective
Last update:
Update count:0
Registration date
2017-01-05, 1395/10/16
Registrant information
Name
Azam Zarneshan
Name of organization / entity
Azarbaijan Shahid Madani University
Country
Iran (Islamic Republic of)
Phone
+98 41 3432 7505
Email address
zarneshan@azaruniv.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice chancellor for research, Urmia University of Medical Sciences and Researcher
Expected recruitment start date
2016-02-20, 1394/12/01
Expected recruitment end date
2016-09-05, 1395/06/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of 12 weeks of aerobic exercise training on sex hormones and blood markers of airway inflammation in mid luteal phase of asthmatics women
Public title
Effect of aerobic exercise training on inflammatory markers and sex hormones in asthmatic women
Purpose
Health service research
Inclusion/Exclusion criteria
Inclusion criteria: mild to moderate asthma; inactive; regular menstrual cycle
and
Exclusion criteria: menstrual disorders; smoking; cardiovascular diseases; other pulmonary diseases
Age
From 25 years old to 42 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
24
Randomization (investigator's opinion)
Not randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethic Committee of Urmia University of Medical Sciences
Street address
Urmia University of Medical Sciences and Health Service, Next Emergency Center, Resalat Blvd
City
Urmia
Postal code
57147833734
Approval date
2016-04-30, 1395/02/11
Ethics committee reference number
ir.umsu.rec.1395.81
Health conditions studied
1
Description of health condition studied
Asthma
ICD-10 code
J45
ICD-10 code description
Asthma
Primary outcomes
1
Description
Eosinophil%
Timepoint
At baseline and after 3 month exercise training
Method of measurement
Blood collection, CBC-PBS
2
Description
IgE
Timepoint
at baseline and after 3 month exercise training
Method of measurement
Blood collection, immunoassay system (Siemens,USA)