Inclusion criteria:
Informed consent to participate in the study
Full consciousness and acceptable verbal and auditory ability to answer the questions
The patient should not suffer from obvious mental disorder and severe mood - emotional disturbance that prevents effective communication
The patient should be in normal neurological and vascular status.
Lack of muscular and skeletal disorders debilitating physical activity
Lack of ulcer and redness in limbs
Patients with chronic renal failure (Patients who have been undergoing hemodialysis for 3 months).
Patients who have an arteriovenous fistula, permanent catheter and arterial-venous graft can access their vessels.
Patients undergoing hemodialysis three times a week and 4 hours each session.
Patients who have had a history of restless leg syndrome during the past 2 months of hemodialysis.
Lack of endocrine disorders (such as hypothyroidism and hyperparathyroidism).
No history of itchy skin diseases
Do not use medicines or foods that they exacerbate the leg syndrome during dialysis, such as: neuroleptics, triangular antidepressants, diphenhydramine, caffeine, alcohol, lithium, beta-blockers, selective serotonin reuptake inhibitors, and serotonin-norepinephrine reuptake inhibitors.
Lack of liver problems
No medication or treatments that affect on restless leg syndrome during dialysis(oral medicines, complementary medicine, acupuncture and topical softeners).
Patients with KT / V ≥1
Patients with hemoglobin 10-11 mg / dL.
Lack of febrile illness and chronic infections (pneumonia, cold during hemodialysis).
Use of bicarbonate dialysis solution
Exclusion criteria:
Patients with catabolic processes such as: malignancies
Diabetic neuropathy
Cases of chronic infections, heart failure, chronic pulmonary disease, severe anemia, coronary artery disease and drug abuse