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Study aim
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Comparison of TIVA and Sevoflurane on changing the results of Pulmonary Function Test (PFT) in patients undergoing inguinal hernia surgery
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Design
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In this interventional study, 18-65 year old patients, with ASA class 1 and 2 who undergo inguinal herniation surgery in the supine position, randomly assign to into two groups consisted of 55 people. Randomization will be done through using permutated blocks.
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Settings and conduct
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During this practical interventional study, patients who meet inclusion criteria will randomly dividing into two 55-member groups. Before starting anesthesia, both groups undergoing spirometry at Kashan Naghavi Hospital and then under the same conditions, they will be under anesthesia induction and monitoring . Then with single-blind way, one group will be undergoing propofol infusion and the second one ,will get anesthesia with sevoflurane. Finally, after being aware completely , patients will perform the spirometry test again in the recovery room and the recorded results will be analyzed.
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Participants/Inclusion and exclusion criteria
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Inclusion criteria: Patients with ASA class 1 & 2, aged 18 to 65 years old, Candidate for unilateral inguinal hernia surgery.
Exclusion criteria: severe cardiovascular diseases, the patient with COPD, chest deformity, liver and kidney failure, and BMI more than 35.
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Intervention groups
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In this study,The subjects of each group,will recieve general anesthesia induction at the same condition, and then ,they will be devided into two groups of 55 members.In the first group those pateint recieving intravenous anesthesia( TIVA), will be infused by propofol and in the second group,anesthesia will be maintained with sevoflorane and N2O until the end of the operation.
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Main outcome variables
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Forced Vital Capacity (FVC);
Forced Expiratory Volum in First second(FEV1);
FEV1 / FVC.