Protocol summary

Study aim
Comparing Face-to-Face and Telephone-Based CBT on Postmenopausal Hot Flushes
Design
This is a randomized clinical trial with two intervention groups of 20 people, community based and pragmatic, with parallel groups and there is no blindness
Settings and conduct
This research will be conducted in the menopausal clinic of Imam Hospital. Our subjects will be selected among eligible registered documents and then women will be invited to participate in this study via phone call .
Participants/Inclusion and exclusion criteria
Inclusion criteria:normal menopause; passing at least one year and maximum five years from the cessation of menstruation; being able to read and write; having at least 10 hot flashes per week in a duration of one month; having a score of more than 1 in response to the kupperman index; having a cell phone. Non-entry criteria: known mental and physical illnesses; history of CBT; drug and other psychotropic substances abuse; under medication for hot flashes
Intervention groups
There will be held six sessions of 30 minutes cognitive-behavioral counseling on a weekly basis for each group.These sessions composed of: providing information about physiology of menopause; introducing cognitive behavioral model (including physiological, cognitive, behavioral and emotional components for hot flashes),teaching breath and relaxation techniques, emphasize the role of stress in boosting hot flashes and cognitive behavioral strategies for reducing it, focus on cognitive responses(Tragedy thoughts and extreme negative beliefs about hot flushes) and behavioral reactions(avoidance and activity) on hot flushes, providing weekly assignments, implementing cognitive behavioral strategies for hot flushes management and breathing techniques and finally, preparing the main list of beliefs, their variability and methods for changing negative beliefs.
Main outcome variables
Hot flushes

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20180918041065N1
Registration date: 2018-11-20, 1397/08/29
Registration timing: retrospective

Last update: 2018-11-20, 1397/08/29
Update count: 0
Registration date
2018-11-20, 1397/08/29
Registrant information
Name
Nasim Sadeghijoola
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 61 3552 2957
Email address
nasim.sadeghijoola@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2018-07-06, 1397/04/15
Expected recruitment end date
2018-09-06, 1397/06/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparing Face-to-Face and Telephone-Based Cognitive Behavioral Therapy on Hot Flushes in Postmenopausal Women
Public title
Cognitive-Behavioral Therapy (CBT) on hot flushes in postmenopausal women
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Normal Menopause Passing at least one year and maximum five years from the cessation of menstruation Being able to read and write Having at least 10 hot flashes per week in a duration of one month Having a score of more than 1 in response to the kupperman index Having a cell phone
Exclusion criteria:
Known Mental and Physical illnesses History of Cognitive Behavioral Therapy(CBT) Drug and other psychotropic substances abuse Under medication for hot flashes
Age
From 40 years old to 60 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 40
Randomization (investigator's opinion)
Randomized
Randomization description
In this study, eligible individuals will be randomly assigned to two groups of telephone counseling (N=20) and face-to-face counseling (N=20) using block randomization (block size: 4 and allocation ratio: 1). For allocation concealment, 20 four digit numbers will be selected for each participant in the telephone group and face-to face group respectively and will be arranged according to the block size. Then in order to hide the allocation, the numbers will be arranged in blocks of opaque envelop, respectively and will be given randomly to eligible individuals by the secretary.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Ahvaz Jundishapur University of Medical Sciences
Street address
Iran, Ahvaz, Golestan Blv, Ahvaz Jundishapur University of Medical Sciences
City
Ahvaz
Province
Khouzestan
Postal code
61357-15794
Approval date
2018-06-30, 1397/04/09
Ethics committee reference number
IR.AJUMS.REC.1397.289

Health conditions studied

1

Description of health condition studied
Hot flushes in Postmenopausal women
ICD-10 code
N95.1
ICD-10 code description
Menopausal and female climacteric states

Primary outcomes

1

Description
Hot flush score in the Kupperman index
Timepoint
Hot flush at baseline, at the end of intervention, six weeks after intervention, and two months after intervention
Method of measurement
Kupperman Index

Secondary outcomes

empty

Intervention groups

1

Description
ّFor the face-to face group, six sessions of 30 minutes each of cognitive-behavioral counseling will be held on a weekly basis for one intervention groups. These sessions composed of the following issues: expression of the rules and objectives of the study, providing information about physiology of menopause as well its complications and treatment, introducing cognitive behavioral model including physiological, cognitive,behavioral and emotional components for hot flashes and night sweats, teaching breath and relaxation techniques, emphasizing the role of stress in boosting hot flashes, night sweats and cognitive behavioral strategies for reducing it, focusing on cognitive responses(tragedy thoughts and extreme negative beliefs about hot flushes) and behavioral reactions(avoidance and activity) on hot flushes, providing weekly assignments, implementing cognitive behavioral strategies for hot flushes management, breathing techniques and relaxation for home work and finally preparing the main list of beliefs and cognition as well as their variability and methods to change negative beliefs.
Category
Treatment - Other

2

Description
For the telephone based counseling, there will be six sessions of 20-30 minutes telephone cognitive-behavioral counseling on a weekly basis. The content of these sessions are as follows: expression of the rules and objectives of the study, providing information on physiology of menopause as well as its complications and treatment, introducing cognitive behavioral model including physiological, cognitive,behavioral and emotional components for hot flashes and night sweats, teaching breath and relaxation techniques, emphasizing the role of stress in boosting hot flashes, night sweats and cognitive behavioral strategies for reducing it, focusing on cognitive responses(tragedy thoughts and extreme negative beliefs about hot flushes) and behavioral reactions(avoidance and activity) on hot flushes, providing weekly assignments, implementing cognitive behavioral strategies for hot flushes management, breathing techniques and relaxation for home work and finally preparing the main list of beliefs and cognition as well as their variability and methods to change negative beliefs.
Category
Treatment - Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Menopause Clinic of Ahvaz Imam Khomeini Hospital
Full name of responsible person
Porandokht Afshary
Street address
Iran, Ahvaz, Azadegan Ave, Imam Khomeini Hospital, Menopause clinic
City
Ahvaz
Province
Khouzestan
Postal code
6193673111
Phone
+98 61 3373 8619
Email
P_afshary@yahoo.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Ahvaz University of Medical Sciences
Full name of responsible person
mohammad badvi
Street address
Ahvaz, Golestan Ave, Ahvaz Jundishapur University of Medical Sciences, Vice-Chancellor for Research of Jundishapur University of Medical Sciences
City
Ahvaz
Province
Khouzestan
Postal code
61357-15794
Phone
+98 61 3336 2414
Fax
+98 61 3336 1544
Email
itc@ajums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Ahvaz University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Ahvaz University of Medical Sciences
Full name of responsible person
Porandokht Afshary
Position
Assistant Professor
Latest degree
Master
Other areas of specialty/work
Midwifery
Street address
Ahvaz, Golestan Ave, Ahvaz Jundishapur University of Medical Sciences, Nursing & Midwifery School, Menopause Research Center
City
Ahvaz
Province
Khouzestan
Postal code
61357-15794
Phone
+98 61 3373 8619
Email
P_afshary@yahoo.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Ahvaz University of Medical Sciences
Full name of responsible person
Porandokht Afshary
Position
Assistant Professor
Latest degree
Master
Other areas of specialty/work
Midwifery
Street address
Ahvaz, Golestan Ave, Ahvaz Jundishapur University of Medical Sciences, Nursing & Midwifery School, Menopause Research Center
City
Ahvaz
Province
Khouzestan
Postal code
61357-15794
Phone
+98 61 3373 8619
Email
P_afshary@yahoo.com

Person responsible for updating data

Contact
Name of organization / entity
Ahvaz University of Medical Sciences
Full name of responsible person
Nasim Sadeghijoola
Position
Student
Latest degree
Bachelor
Other areas of specialty/work
Midwifery
Street address
No.41, West khajenejad Ave., Zibashahr Blvd., Ahvaz Town
City
Ahvaz
Province
Khouzestan
Postal code
6184734444
Phone
+98 61 3552 2957
Fax
Email
sadeghijoola.n@ajums.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
Yes - There is a plan to make this available
Data Dictionary
Yes - There is a plan to make this available
Title and more details about the data/document
The entire data can be shared after anonymize participants
When the data will become available and for how long
Data can be accessed after publication for a period of one year.
To whom data/document is available
Only for scholars working in the scientific institution
Under which criteria data/document could be used
The data are available upon referencing name of investigators, clinical trials and research
From where data/document is obtainable
Pourandokht Afshary, Faculty Member of Ahvaz Jundishapur University of Medical Sciences Email: P_afshary@yahoo.com
What processes are involved for a request to access data/document
Send the request via email,will be answered as soon as possible
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