Inclusion criteria:
Hospitalization in the internal part for at least 48 hours, voluntary participation in the study, 20 to 70 years of age, having a healthy upper limb, requiring 48 hours of intravenous catheter, absence of phlebitis in the site before insertion of the angioquate, failure to receive injurious medications to the artery wall (Diazepam, midazolam, amiodarone, vitamin C, levofloxacin and ciprofloxacin), non-use of anticoagulants, the use of alcohol as an antiseptic prior to the administration of the catheter, as well as a history of vascular, systemic, diabetes, skin disease, diseases Acute and severe infections, severe anemia, glaucoma, hypotension (systolic pressure less than 100 mm) More mercury). Immune deficiency, no chemotherapy, no intravenous feeding. The type of catheter is angioquate and not attached to heparin lacquer.
Exclusion criteria:
Conditions for not admitting to the study: discharge from the hospital two days after the start of the intervention, unwillingness to continue cooperation in the study, lack of proper and timely use of the Aloe vera and nitroglycerine ointment during the study, rupture or withdrawal of the angiocontection before 48 hours , Getting sick for any reason and getting the intravenous line in the same.