The aim of this triple-blind randomized controlled trial with two parallel arms is to determine the effect of ethanol extract of Iranian borage (Echium amoenum) on pain intensity and quality of life enjoyment and satisfaction (primary outcomes) and menstrual bleeding (secondary outcome). Visual analogue scale, quality of life enjoyment and satisfaction questionnaire and Higham chart will be used to assess the outcomes, respectively. After signing an informed consent, all selected eligible students with moderate to severe primary dysmenorrhea living in Tabriz student dormitories will be asked to take identical analgesic (gelofen capsules) for menstrual pain relief, if needed. They will be asked to record their menstrual pain, number of analgesics used, the quality of life and menstrual blood loss in the following cycle (running period). 70 of them, who had good cooperation, will be allocated into two groups using block randomization with block size of 4 and 6 and allocation ratio of 1:1, stratified by dormitory. Consecutive numbered packs, each containing 18 identical capsules of 500 mg Echium amoenum or placebo will be used for the blinding. Each participant will get one of the packs in their recruitment rank, to use the capsules every 12 hours since onset of menstrual pain for 72 hours or until the pain relief, for three following cycles. They will be asked to record the capsule use and any side effects on a diary, in addition to recording menstrual pain, number of the gelofen used, the quality of life and menstrual blood loss, in the three cycles.