Protocol summary

Study aim
Comparative study of the effect of lower limb constraint induced movement therapy with conventional physical therapy on gait kinematics and functional tests in hemiparetic patients
Design
Randomized comparative study, with experimental and control groups, parallel, single blinded, randomized via block randomization with 15 participants in each group
Settings and conduct
This study was conducted in Qaem hospital in Mashhad. Patients with stroke in experimental group received constraint induced movement therapy via a shoe lift with 6mm thickness in conjunction with conventional physiotherapy. Patients in control group received only conventional physiotherapy. The outcome measures of the study included gait kinematics and functional tests which were recorded before and after intervention in each group and then were compared between the two groups. Persons who were involved in collecting and analyzing of data were blinded to group allocation.
Participants/Inclusion and exclusion criteria
1) Age range of 40-70 years 2) First ever stroke 3) Unilateral hemiparesis 4) Chronic stroke 5) Modified Ashworth Scale < or = 2 6) ability to walk without assistive device 7) weight bearing asymmetry
Intervention groups
Experimental group: constraint induced movement therapy in conjunction with conventional physiotherapy Control group: conventional physiotherapy
Main outcome variables
Weight bearing asymmetry- ‍COP velocity changes- Spatial temporal gait measures- The changes of angular velocity of the lower limb joints during gait- Berg Balance Scale- Timed up and go

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20190603043808N1
Registration date: 2019-07-24, 1398/05/02
Registration timing: retrospective

Last update: 2019-07-24, 1398/05/02
Update count: 0
Registration date
2019-07-24, 1398/05/02
Registrant information
Name
Hossein Asghar Hosseini
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 51 3884 6710
Email address
hosseiniha@mums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2011-08-19, 1390/05/28
Expected recruitment end date
2012-08-18, 1391/05/28
Actual recruitment start date
2011-08-19, 1390/05/28
Actual recruitment end date
2012-08-18, 1391/05/28
Trial completion date
2012-11-18, 1391/08/28
Scientific title
Effect of " constraint induced movement therapy " of lower limb on gait kinematics and functional test of lower limbs in hemiparetic patients
Public title
Effect of constraint induced movement therapy in hemiparetic patients
Purpose
Health service research
Inclusion/Exclusion criteria
Inclusion criteria:
Age range of 40-70 First ever stroke Chronic unilateral hemiparesis Modified Ashworth Scale < or = 2 Ability to walk without asisstive device Weight bearing asymmetry
Exclusion criteria:
Bilateral hemiparesis Occiput and limbic system lesions Cognitive impairments Aphasia Any neurologic condition in addition to stroke Any orthopedic condition that could affect walking pattern
Age
From 40 years old to 70 years old
Gender
Both
Phase
N/A
Groups that have been masked
  • Outcome assessor
  • Data analyser
  • Data and Safety Monitoring Board
Sample size
Target sample size: 30
Actual sample size reached: 30
Randomization (investigator's opinion)
Randomized
Randomization description
Block randomization
Blinding (investigator's opinion)
Single blinded
Blinding description
Personnel who collect and analyse the outcome measures were blinded to study.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Mashhad University of Medical Sciences
Street address
Vice-Chancellor for research, Ghorashi Building, University street
City
Mashhad
Province
Razavi Khorasan
Postal code
91388-13944
Approval date
2011-06-18, 1390/03/28
Ethics committee reference number
98/67031

Health conditions studied

1

Description of health condition studied
Stroke
ICD-10 code
I 67.9
ICD-10 code description
Cerebrovascular disease, unspecified syndrome, cerebellar, stroke

Primary outcomes

1

Description
Weight bearing asymmetry index
Timepoint
Before and after intervention
Method of measurement
Force platform

2

Description
Spatio-temporal gait parameters
Timepoint
Before and after intervention
Method of measurement
Video camera

3

Description
‍COP velocity
Timepoint
Before and after intervention
Method of measurement
Force platform

4

Description
Joints angular velocity
Timepoint
Before and after intervention
Method of measurement
Video camera

5

Description
Berg Balance Scale
Timepoint
Before and after intervention
Method of measurement
Questionnaire

Secondary outcomes

1

Description
Timed up & go
Timepoint
Before and after intervention
Method of measurement
Chronometer

Intervention groups

1

Description
"Experimental group": Patients in Experimental group received lower limbs constraint induce movement therapy (via a 6 mm shoe lift under the non-paretic leg) in conjunction with conventional physiotherapy for 6 weeks."
Category
Rehabilitation

2

Description
"Control group:Patients in Control group only received conventional physiotherapy for 6 weeks."
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Quaem hospital
Full name of responsible person
Hossein Asghar Hosseini
Street address
Rehabilitation ward, Quaem hospital, Ahmadabad Ave.
City
Mashhad
Province
Razavi Khorasan
Postal code
99199-91766
Phone
+98 51 3844 2242
Fax
+98 51 3845 3239
Email
Hosseiniha@mums.ac.ir
Web page address
http://quaem.mums.ac.ir/

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Mohsen Tafaghodi
Street address
Vice-Chancellor for research, Gorashi building, University Ave.
City
Mashhad
Province
Razavi Khorasan
Postal code
91388-13944
Phone
+98 51 3841 2081
Fax
+98 51 3841 3006
Email
vcresearch@mums.ac.ir
Web page address
http://v-research.mums.ac.ir/
Grant name
Research grant
Grant code / Reference number
511/1278
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Mashhad University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Hossein Asghar Hosseini
Position
Assistant professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiotherapy
Street address
Physiotherapy department, Paramedical sciences faculty, University campus, Azadi square
City
Mashhad
Province
Razavi Khorasan
Postal code
9177948964
Phone
+98 51 3884 6710
Fax
+98 51 3884 6728
Email
Hosseiniha@mums.ac.ir
Web page address
http://sps.mums.ac.ir/

Person responsible for scientific inquiries

Contact
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Hossein Asghar Hosseini
Position
Assistant professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiotherapy
Street address
Physiotherapy department, Paramedical sciences faculty, University campus, Azadi square
City
Mashhad
Province
Razavi Khorasan
Postal code
9177948964
Phone
+98 51 3884 6710
Fax
+98 51 3884 6728
Email
Hosseiniha@mums.ac.ir
Web page address
http://sps.mums.ac.ir/

Person responsible for updating data

Contact
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Hossein Asghar Hosseini
Position
Assistant professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiotherapy
Street address
Physical therapy department,Faculty of paramedical Sciences,University campus,Azadi square
City
Mashhad
Province
Razavi Khorasan
Postal code
9177948964
Phone
+98 51 3884 6710
Fax
+98 51 3884 6728
Email
hosseiniha@mums.ac.ir
Web page address
http://sps.mums.ac.ir/

Sharing plan

Deidentified Individual Participant Data Set (IPD)
No - There is not a plan to make this available
Justification/reason for indecision/not sharing IPD
No more information.
Study Protocol
No - There is not a plan to make this available
Statistical Analysis Plan
No - There is not a plan to make this available
Informed Consent Form
No - There is not a plan to make this available
Clinical Study Report
No - There is not a plan to make this available
Analytic Code
Not applicable
Data Dictionary
Not applicable
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