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Protocol summary

Study aim
The effects of routine treatment and manual therapy in patients with temporomandibular disorders
Design
This study included two groups: control group and intervention group. study design: randomized control trial with control group, parallel group. The patients and outcome assessor will be blind
Settings and conduct
Place of study: Iran University of Medical Sciences, School of rehabilitation, Ultrasonography laboratory Method: This study included two groups: control group and intervention group. Control group: The control group will receive the routine physiotherapy including gentle massage over the masseter muscle, ultrasound 1 MHz and TENS. The intervention group will receive the routine physiotherapy AND manual therapy of temporomandibular joint and upper cervical .
Participants/Inclusion and exclusion criteria
Inclusion criteria: 1-unilateral or bilateral TMD according to the DC/TMD 2-pain more than 3 based on visual analog scale Exclusion criteria: 1-a traumatic injury that caused the symptoms in the temporomandibular joint and the orofacial region during the last three months 2-history of the orofacial surgery during the last 6 months 3-neurological and systemic diseases such as rheumatoid arthritis; Parkinson; multiple sclerosis, positional vertigo, pregnancy, and severe deformity in the jaw or face region
Intervention groups
Control group: The control group will receive the routine physiotherapy such as massage, therapeutic ultrasound 1MHZ and TENS for eight weeks. Intervention group: The intervention group will receive the routine physiotherapy and manual therapy of TMJ and cervical spine. The patients in both groups will receive routine physiotherapy 10 sessions during eight weeks.
Main outcome variables
pain; maximum mouth opening, cervical flexion and extension range of motions,

General information

Reason for update
Lack of time in coronary conditions
Acronym
IRCT registration information
IRCT registration number: IRCT20190621043964N1
Registration date: 2019-06-29, 1398/04/08
Registration timing: prospective

Last update: 2021-07-19, 1400/04/28
Update count: 1
Registration date
2019-06-29, 1398/04/08
Registrant information
Name
Khaled Rezaie
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 21 2222 8051
Email address
rezaie.kh@iums.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2019-11-01, 1398/08/10
Expected recruitment end date
2021-02-01, 1399/11/13
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effects of routine treatment and manual therapy on pain, and range of motion in patients with temporomandibular disorders
Public title
The effects of routine treatment and manual therapy in people with temporomandibular disorder
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Individuals with tunilateral or bilateral TMD according to the DC/TMD pain more than 3 based on visual analog scale
Exclusion criteria:
traumatic injury that caused the symptoms in the temporomandibular joint and the orofacial region during the last three months history of the orofacial surgery during the last 6 months neurological and systemic diseases such as rheumatoid arthritis; Parkinson; multiple sclerosis, positional vertigo, pregnancy, and severe deformity in the jaw or face region
Age
From 20 years old to 50 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 30
Randomization (investigator's opinion)
Randomized
Randomization description
Randomization method: Block balanced randomization design, block size:4, ratio 1:1 Randomization tool: Random allocation will be performed using the website of www.randomization.com.
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Iran University of Medical Sciences
Street address
Iran University of Medical Sciences, Shahid Hemmat Highway, Tehran
City
Tehran
Province
Tehran
Postal code
۱۴۴۹۶۱۴۵۳۵
Approval date
2018-10-28, 1397/08/06
Ethics committee reference number
Ir.Iums.Rec.1397.1054

Health conditions studied

1

Description of health condition studied
Temporomandibular dysfunction
ICD-10 code
M26.6
ICD-10 code description
Temporomandibular joint disorders

Primary outcomes

1

Description
pain
Timepoint
At the baseline, after the end of the treatment, and after a one-month follow-up period
Method of measurement
Visual analog scale

Secondary outcomes

1

Description
Maximum mouth opening
Timepoint
At the baseline, after the end of the treatment, and after a one-month follow-up period
Method of measurement
caliper

2

Description
Cervical flexion and extension ROM
Timepoint
At the baseline, after the end of the treatment, and after a one-month follow-up period
Method of measurement
Goniometer

Intervention groups

1

Description
Control group: The control group will receive the routine physiotherapy such as gentle massage over the masseter muscles , therapeutic ultrasound 1MHZ and TENS for ten sessions during 8 weeks.
Category
Rehabilitation

2

Description
Intervention group: The intervention group will receive the routine physiotherapy such as gentle massage over the masseter muscles , therapeutic ultrasound 1MHZ and TENS and manual therapy of the TMJ and upper cervical spine. This group will receive the interventions for ten sessions during 8 weeks.
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Shariati hospital
Full name of responsible person
Khaled Rezaie
Street address
Shariati Shariati Hospital, Jalal-e-Al-e-Ahmad Hwy, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1411713135
Phone
+98 21 8490 1000
Fax
+98 21 8863 3039
Email
rezaie.kh@iums.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Dr. Malakooti Seyyed Kazem
Street address
Iran University of Medical Sciences, Shahid Hemmat Highway, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1348715459
Phone
+98 21 86701
Email
PR@iums.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Iran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Rezaie Khaled
Position
Phd student of Physiotherapy, Iran University of Medical Sciences
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
Maddadkaran St., Shahid Nazari St., Mother Square, Mirdamad Blvd, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1348715459
Phone
+98 21222280512
Email
rezaie.kh@iums.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Amiri Ali
Position
Associate professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiotherapy
Street address
Maddadkaran St., Shahid Nazari St., Mother Square, Mirdamad Blvd, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1348715459
Phone
+98 21 2222 7124
Email
amiri.alipt10@yahoo.com

Person responsible for updating data

Contact
Name of organization / entity
Iran University of Medical Sciences
Full name of responsible person
Rezaie Khaled
Position
Phd student of Physiotherapy, Iran University of Medical Sciences
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
Maddadkaran St., Shahid Nazari St., Mother Square, Mirdamad Blvd, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran
City
Tehran
Province
Tehran
Postal code
1348715459
Phone
+98 21222280512
Email
rezaie.kh@iums.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Yes - There is a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Not applicable
Analytic Code
Not applicable
Data Dictionary
Not applicable
Title and more details about the data/document
The original data is shared in thesis format
When the data will become available and for how long
After defense of thesis, the original data is shared in thesis format.
To whom data/document is available
Academic researchers, physiotherapists
Under which criteria data/document could be used
In order to use clinical results, the original data is shared in thesis format.
From where data/document is obtainable
Library of the faculty of rehabilitation rehabilitation Sciences of Iran University of Medical Sciences
What processes are involved for a request to access data/document
Referral to library of the faculty of rehabilitation Sciences of Iran University of Medical Sciences
Comments
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