Protocol summary

Study aim
Effect of 6-week strength-balance training under virtual reality environment on the co-contraction of lower limb muscles and center of pressure sway during limit of stability, curve tracking and turning in women with primary osteoporosis
Design
Clinical trial with intervention and control groups, parallel group, double-blind, randomized groups using random number table
Settings and conduct
The study will be conducted at Tarbiat Modares University's Gait Lab on women with primary osteoporosis. Intervention group will perform 6-weeks of strength-balance training using active video games via the Xbox 360 Kinect. control group will also perform 6 weeks of specific strength-balance training using the pulley and tilt board. In both groups, the effects of training on lower extremity muscle cocontraction and center of pressure sway after treatment will be examined.Individuals in each study groups were not aware of the type of exercise in the other group. The assessor is also blind to the allocation of study groups.
Participants/Inclusion and exclusion criteria
Inclusion criteria؛ Women with primary osteoporosis after menopause Age range 48-65 At least one year has passed since the onset of menopause Not participating in regular exercise Obtain the normal score from the Mini mental exam Questionnaire Exclusion criteria؛ Vision problems A history of osteoporosis fractures Balance problems such as sudden falls Secondary osteoporosis
Intervention groups
Intervention group: 6 weeks strength-balance training under virtual reality environment Control group: 6 weeks of dedicated, lightweight strength-balance training using Polley and Tilt Board
Main outcome variables
Muscle strength; quality of life and fear of falling score؛ RMS؛ Coactivation index؛ LOS(reaction time)؛ Curve tracking(RMS error)؛Curve tracking(area)؛ Curve tracking(mean frequency)؛ Curve tracking(peak frequency)؛ Turning (turning sway)

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20101017004952N9
Registration date: 2019-11-30, 1398/09/09
Registration timing: registered_while_recruiting

Last update: 2019-11-30, 1398/09/09
Update count: 0
Registration date
2019-11-30, 1398/09/09
Registrant information
Name
Giti Torkaman
Name of organization / entity
Tarbiat Modares University
Country
Iran (Islamic Republic of)
Phone
+98 21 8288 4509
Email address
torkamg@modares.ac.ir
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2019-10-22, 1398/07/30
Expected recruitment end date
2020-07-21, 1399/04/31
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of 6-week strength-balance training under virtual reality environment on the co-contraction of lower limb muscles and center of pressure sway during limit of stability, curve tracking and turning in women with primary osteoporosis
Public title
Effect of training under virtual reality environment on the co-contraction of lower limb muscles and center of pressure sway
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
BMI 22-30 kg / m 2 At least one year after menopause Not participating in regular exercise Not being on hormone therapy for at least the past 6 months No musculoskeletal and neurological problems Obtain the normal score from the Mini mental state exam Age range 48-65
Exclusion criteria:
Balance problems such as sudden falls A history of osteoporotic fractures Vision problems Use of walking aids
Age
From 48 years old to 65 years old
Gender
Female
Phase
N/A
Groups that have been masked
  • Outcome assessor
Sample size
Target sample size: 20
Randomization (investigator's opinion)
Randomized
Randomization description
Randomization will be done by an independent person by blocking randomization using sealed, opaque, and stapled envelopes
Blinding (investigator's opinion)
Single blinded
Blinding description
Participants in each group are not aware of the other group program. The assessor or data collector is blinded about grouping.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Tarbiat modares university
Street address
Jalale ale ahmad., nasr bridge., chamran highway
City
Tehran
Province
Tehran
Postal code
14115-111
Approval date
2019-11-04, 1398/08/13
Ethics committee reference number
IR.MODARES.REC.1398.151

Health conditions studied

1

Description of health condition studied
postmenopausal osteoporosis
ICD-10 code
m81.9
ICD-10 code description
Postmenopausal osteoporosis

Primary outcomes

1

Description
ٍEMG and Co-contracting index of muscles in functional activities
Timepoint
The timing of measurements will be before the start of the intervention and after 6 weeks of strength-balance training.
Method of measurement
Electromyography system

2

Description
CoP sway in functional activities
Timepoint
The timing of measurements will be before the start of the intervention and after 6 weeks of strength-balance training.
Method of measurement
mars software and force plate

Secondary outcomes

1

Description
Quality of Life Score
Timepoint
The variables will be measured at baseline and also after 6 weeks of strength-balance training.
Method of measurement
Qualeffo-41 Questionnaire, Fall Efficacy Scale Questionnaire

2

Description
Muscle strength
Timepoint
The variables will be measured at baseline and also after 6 weeks of strength-balance training.
Method of measurement
Digital hand-held dynamometer

Intervention groups

1

Description
Intervention group: 6 weeks of 3 sessions of strength-balance training under virtual reality environments through active video games using the Xbox kinect 360 Console
Category
Rehabilitation

2

Description
Control group: Performing specific, lightweight strength-balance training for 3 days a week for 6 weeks using a pulley and tilt board
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
Tarbiat Modares University
Full name of responsible person
ِDr. Giti Torkaman
Street address
Jala AleAhmad Ave., Nasr
City
Tehran
Province
Tehran
Postal code
1411713116
Phone
+98 21 8288 4509
Email
torkamg@modares.ac.ir

2

Recruitment center
Name of recruitment center
Baqiyatallah Al'Azam Hospital
Full name of responsible person
Noushin Bayat
Street address
Vanak Square, Mulla Sadra Street, after Sheikh Bahayi, Baqiyatallah Al'Azam Hospital
City
Tehran
Province
Tehran
Postal code
1435915371
Phone
+98 21 8805 0436
Email
mohammad.gilani@modares.ac.ir

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Tarbiat Modares University
Full name of responsible person
Yaghoub Fatholahi
Street address
Jala AleAhmad Ave., Nasr
City
Tehran
Province
Tehran
Postal code
1411713116
Phone
+98 21 8288 2009
Fax
+98 21 8800 6544
Email
pres@modares.ac.ir
Web page address
http://www.modares.ac.ir
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tarbiat Modares University
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Tarbiat Modares University
Full name of responsible person
Dr Giti Torkaman
Position
professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiotherapy
Street address
Jalal AleAhmad Ave., Nasr
City
Tehran
Province
Tehran
Postal code
1411713116
Phone
+98 21 8288 4509
Email
torkamg@modares.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Tarbiat Modares University
Full name of responsible person
Dr Giti Torkaman
Position
professor
Latest degree
Ph.D.
Other areas of specialty/work
Physiotherapy
Street address
Jalal AleAhmad Ave, Nasr
City
Tehran
Province
Tehran
Postal code
1411713116
Phone
+98 21 8288 0000
Email
torkamg@modares.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
Tarbiat Modares University
Full name of responsible person
Mohammad Gilani
Position
PhD candidate
Latest degree
Master
Other areas of specialty/work
Physiotherapy
Street address
Jalal AleAhmad Ave, Nasr
City
Tehran
Province
Tehran
Postal code
1411713116
Phone
+98 21 8288 0000
Email
mohammad.gilani@modares.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Yes - There is a plan to make this available
Statistical Analysis Plan
Undecided - It is not yet known if there will be a plan to make this available
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Yes - There is a plan to make this available
Analytic Code
No - There is not a plan to make this available
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
All data will be shared after confirmation of chief researcher.
When the data will become available and for how long
6 months after publication
To whom data/document is available
All researchers
Under which criteria data/document could be used
For scientific purposes
From where data/document is obtainable
Dr. Giti Torkaman
What processes are involved for a request to access data/document
Confirmation of chief researcher
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