EFFECTS OF QUADRICEPS KINETIC EXERCISES AT SPECIFIC KNEE ANGLE IN PATIENTS WITH POST-SURGICAL ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION: A RANDOMIZED CONTROLLED TRIAL
To examine the effects of specific quadriceps open and closed chain on knee function (pain, knee function, ROM and recurrence of ACL) after anterior cruciate ligament reconstruction surgery.
Design
Parallel group single blind randomized controlled trial
Settings and conduct
Physical Therapy Department, Northwest General Hospital & Research Center Peshawar, Pakistan and Rehman Medical Institute Peshawar, Pakistan.
Participants/Inclusion and exclusion criteria
Inclusion Criteria:
Age: 20-50 years,
Both Gender
Patients having Unilateral Anterior Cruciate Ligament reconstruction
Healthy Contralateral leg
ACL reconstruction surgery
Ability to walk with or without an assistive device
Exclusion Criteria:
Any previous knee injury
History of dislocation hip
Concomitant injury
Posterior Cruciate ligament Tear
Any rheumatologic conditions
Any trauma or meniscus injury
History of Ligamentous instability at knee
History of referred pain from the lumbar spine, hip, pelvis and sacroiliac regions
Patients with history of remarkable knee joint inflammation and effusion,
Patients with history of Hyperextension of knee joint
Patients with history of polio paralysis
Previous History of physiotherapy session for knee treatment
Intervention groups
Group-A:
consisting of Controlled alternate quad and hamstring activity in open kinematic chain (OKC) plus Routine Physical Therapy
Group-B:
consisting of Controlled squats in closed kinematic chain (CKC) plus Routine Physical Therapy
Group-C: (Combined Group)
consisting of Controlled squats in closed kinematic chain (CKC) & controlled alternate quad and hamstring activity in open kinematic chain (OKC) plus Routine Physical Therapy
All groups will get 60 Minute session, 3 days a week alternatively for 12 weeks
Main outcome variables
Pain
Knee Function
Range of Motion
Recurrence of ACL
General information
Reason for update
Acronym
IRCT registration information
IRCT registration number:IRCT20200331046903N1
Registration date:2020-04-21, 1399/02/02
Registration timing:registered_while_recruiting
Last update:2020-04-21, 1399/02/02
Update count:0
Registration date
2020-04-21, 1399/02/02
Registrant information
Name
Danish Ali Khan
Name of organization / entity
University of lahore
Country
Pakistan
Phone
+92 91 5813805
Email address
dani_ak_pk@hotmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2020-04-15, 1399/01/27
Expected recruitment end date
2020-10-15, 1399/07/24
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
EFFECTS OF QUADRICEPS KINETIC EXERCISES AT SPECIFIC KNEE ANGLE IN PATIENTS WITH POST-SURGICAL ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION: A RANDOMIZED CONTROLLED TRIAL
Public title
EFFECTS OF QUADRICEPS KINETIC EXERCISES AT SPECIFIC KNEE ANGLE IN PATIENTS WITH POST-SURGICAL ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION: A RANDOMIZED CONTROLLED TRIAL
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Patients aged 20-50 years
Both male and female patients
Patients having Unilateral Anterior Cruciate Ligament reconstruction
Healthy Contralateral leg
ACL reconstruction surgery
Ability to walk with or without an assistive device
Exclusion criteria:
Any previous knee injury
History of dislocation hip
Concomitant injury
Posterior Cruciate ligament Tear
Any rheumatologic conditions (osteoarthritis, rheumatoid arthritis),
Any trauma or meniscus injury
History of Ligamentous instability at knee
History of referred pain from the lumbar spine, hip, pelvis and sacroiliac regions
Patients with history of remarkable knee joint inflammation and effusion,
Patients with history of Hyperextension of knee joint
Patients with history of polio paralysis
Previous History of physiotherapy session for knee treatment
Age
From 20 years old to 50 years old
Gender
Both
Phase
N/A
Groups that have been masked
Outcome assessor
Sample size
Target sample size:
54
Randomization (investigator's opinion)
Randomized
Randomization description
The subject fulfilling the inclusion criteria will be enrolled by independent outcome assessor then lottery method will be used for randomization. Each member of the population will be number systematically and in consequent manner by writing each number on a separate piece of paper. These pieces of paper are mixed and put into a box and then numbers are drawn out of the box in a random manner. The subject’s randomization method will reduce the chances of group bias allocation.
Blinding (investigator's opinion)
Single blinded
Blinding description
The study is single blinded in which outcome assessor will be kept blind
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Institutional Review Board of University Institute of Physical therapy University of Lahore
Street address
1- Km Raiwind Rd, Sultan Town, Lahore, Punjab
City
Lahore
Postal code
54792
Approval date
2020-01-22, 1398/11/02
Ethics committee reference number
IRB-UOL-FAHS/695/2020
Health conditions studied
1
Description of health condition studied
Anterior Cruciate ligament Reconstruction
ICD-10 code
S83.519A
ICD-10 code description
Sprain of anterior cruciate ligament of unspecified knee, initial encounter
Primary outcomes
1
Description
Pain
Timepoint
before intervention and 6, 12 and 24 weeks after intervention
Method of measurement
Visual Analogue Scale
2
Description
Knee Function
Timepoint
before intervention and 6, 12 and 24 weeks after intervention
Method of measurement
Lysholm Knee Scoring scale
3
Description
Range of Motion
Timepoint
before intervention and 6, 12 and 24 weeks after intervention
Method of measurement
Goniometer
4
Description
Recurrence of Anterior Cruciate Ligament
Timepoint
before intervention and 6, 12 and 24 weeks after intervention
Method of measurement
Lachman Test
Secondary outcomes
empty
Intervention groups
1
Description
Intervention group 1. Patients in this study group will get 60 Minute session, 3 days a week alternatively for 12 weeks consisting of Controlled alternate quad and hamstring activity in open kinematic chain (OKC) + Routine Physical Therapy, Modalities and Exercise for other body parts including contralateral lower limb, trunk, upper limbs, respiratory exercises.
Category
Treatment - Other
2
Description
Intervention group 2. Patients in this study group will get 60 Minute session, 3 days a week alternatively for 12 weeks consisting of Controlled squats in closed kinematic chain (CKC) + Routine Physical Therapy, Modalities and Exercise for other body parts including contralateral lower limb, trunk, upper limbs, respiratory exercises.
Category
Treatment - Other
3
Description
Intervention group 3. Patients in this study group will get 60 Minute session, 3 days a week alternatively for 12 weeks consisting of Controlled squats in closed kinematic chain (CKC) & controlled alternate quad and hamstring activity in open kinematic chain (OKC) + Routine Physical Therapy, Modalities and Exercise for other body parts including contralateral lower limb, trunk, upper limbs, respiratory exercises.
Category
Treatment - Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Physical Therapy Department Northwest General Hospital and Research Center , Peshawar, KPK, Pakistan