Protocol summary

Study aim
Comparing cervical foley catheter and vaginal misoprostol in simplification of labor delivery
Design
This study is a randomized clinical trial which was conducted in the delivery and women hospital of Bandar- Abbas in 2016-2017. In this study 120 randomized postdate primigravid women between 18-35 yeares old who suffered from vaginal bleeding, abnormal fetal heartbeat, natural disease that needed to terminate the pregnancy season, misoprostol susceptibility and weren't utrine scar were selected. They were randomly divided into two groups of 60. In one group cervical foley catheter and in another one vaginal misoprostol 25 microgram was used.
Settings and conduct
This study is a randomized clinical trial which was conducted in the delivery and women hospital of Bandar- Abbas in 2016-2017. In this study 120 randomized postdate primigravid women between 18-35 yeares old who suffered from vaginal bleeding, abnormal fetal heartbeat, natural disease that needed to terminate the pregnancy season, misoprostol susceptibility and weren't utrine scar were selected. They were randomly divided into two groups of 60. In one group cervical foley catheter and in another one vaginal misoprostol 25 microgram was used. In terms of delivery progress need of oxytocin, Apgar score, delivery time, NICU requirement, meconium- stained amniotic fluid were examined. T
Participants/Inclusion and exclusion criteria
In this study 120 randomized postdate primigravid women between 18-35 yeares old who suffered from vaginal bleeding, abnormal fetal heartbeat, natural disease that needed to terminate the pregnancy season, misoprostol susceptibility and weren't utrine scar were selected.
Intervention groups
In one group cervical foley catheter and in another one vaginal misoprostol 25 microgram was used.
Main outcome variables
Time of normal vaginal delivery

General information

Reason for update
Acronym
IRCT registration information
IRCT registration number: IRCT20181218042033N4
Registration date: 2020-04-19, 1399/01/31
Registration timing: retrospective

Last update: 2020-04-19, 1399/01/31
Update count: 0
Registration date
2020-04-19, 1399/01/31
Registrant information
Name
Nazanin Abdi
Name of organization / entity
Country
Iran (Islamic Republic of)
Phone
+98 76 3333 3280
Email address
abdinazanin834@gmail.com
Recruitment status
Recruitment complete
Funding source
Expected recruitment start date
2017-08-15, 1396/05/24
Expected recruitment end date
2018-03-18, 1396/12/27
Actual recruitment start date
2017-08-15, 1396/05/24
Actual recruitment end date
2018-03-18, 1396/12/27
Trial completion date
2018-03-18, 1396/12/27
Scientific title
Comparison of vaginal misoprostol and intra cervical foleycatheter for cervical ripening of postdate primigravid women
Public title
Comparison of vaginal misoprostol and intra cervical foleycatheter for cervical ripening
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:
Primigravid women 18-35 yeares old Vaginal bleeding Abnormal fetal heartbeat Natural disease that needed to terminate the pregnancy season
Exclusion criteria:
Misoprostol susceptibility Uterine scar
Age
From 18 years old to 35 years old
Gender
Female
Phase
N/A
Groups that have been masked
  • Participant
Sample size
Target sample size: 120
Actual sample size reached: 120
Randomization (investigator's opinion)
Randomized
Randomization description
Randomization method: use block; Random unit: Individual; Randomization tool: Statistical software Minitab; Sequence Building: Using randomized 4 in 4 blocks; Hiding method: Use similar bottles
Blinding (investigator's opinion)
Single blinded
Blinding description
Our colleague in this study in hospital delivered formulations to the participants of the study according to the randomized block table.
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Homozgan University of medical sciences
Street address
Hormozgan University Of Medical Sciences, Chamran Blvd, Bandar abbas
City
Shiraz
Province
Fars
Postal code
7916839319
Approval date
2017-08-15, 1396/05/24
Ethics committee reference number
IR.HUMS.REC.1396.85

Health conditions studied

1

Description of health condition studied
Spontaneous delivery
ICD-10 code
O80.0
ICD-10 code description
Encounter for full-term uncomplicated delivery

Primary outcomes

1

Description
Cervical dilatation
Timepoint
Every 6 hours
Method of measurement
Vaginal examination

Secondary outcomes

empty

Intervention groups

1

Description
Intervention group: vaginal misoprostol 25 microgram
Category
Treatment - Drugs

2

Description
Intervention group: cervical foley catheter
Category
Treatment - Devices

Recruitment centers

1

Recruitment center
Name of recruitment center
Hormozgan University of Medical Sciences
Full name of responsible person
Naznin Abdi
Street address
Hormozgan University Of Medical Sciences, Chamran Blvd, Bandar abbas
City
Bandar abbas
Province
Hormozgan
Postal code
7916839319
Phone
+98 71 3647 9830
Email
abdinazanin834@gmail.com

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Bandare-abbas University of Medical Sciences
Full name of responsible person
Abdolazim Nejati Zadeh
Street address
Hormozgan University Of Medical Sciences, Chamran Blvd, Bandar abbas
City
Bandar abbas
Province
Hormozgan
Postal code
7916839319
Phone
+98 76 3647 9830
Email
azimnejate@yahoo.com
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Bandare-abbas University of Medical Sciences
Proportion provided by this source
100
Public or private sector
Public
Domestic or foreign origin
Domestic
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
Academic

Person responsible for general inquiries

Contact
Name of organization / entity
Bandare-abbas University of Medical Sciences
Full name of responsible person
Foroogh Pakbaz
Position
Resedient
Latest degree
Specialist
Other areas of specialty/work
Gynecology and Obstetrics
Street address
Hormozgan University Of Medical Sciences, Chamran Blvd, Bandar abbas
City
Bandar abbas
Province
Hormozgan
Postal code
7916839319
Phone
+98 76 3647 9830
Email
forooghpakbaz@gmail.com

Person responsible for scientific inquiries

Contact
Name of organization / entity
Bandare-abbas University of Medical Sciences
Full name of responsible person
Nazanin Abdi
Position
Assistant professor
Latest degree
Specialist
Other areas of specialty/work
Gynecology and Obstetrics
Street address
Hormozgan University Of Medical Sciences, Chamran Blvd, Bandar abbas
City
Bandar Abbas
Province
Fars
Postal code
7916839319
Phone
+98 736479830
Email
abdinazanin834@gmail.com

Person responsible for updating data

Contact
Name of organization / entity
Bandare-abbas University of Medical Sciences
Full name of responsible person
Nazanin Abdi
Position
Assisstant Professor
Latest degree
Specialist
Other areas of specialty/work
Gynecology and Obstetrics
Street address
Hormozgan University Of Medical Sciences, Chamran Blvd, Bandar abbas
City
Bandar Abbas
Province
Hormozgan
Postal code
7916839319
Phone
+98 36479830
Email
abdinazanin834@gmail.com

Sharing plan

Deidentified Individual Participant Data Set (IPD)
Yes - There is a plan to make this available
Study Protocol
Undecided - It is not yet known if there will be a plan to make this available
Statistical Analysis Plan
Not applicable
Informed Consent Form
Yes - There is a plan to make this available
Clinical Study Report
Undecided - It is not yet known if there will be a plan to make this available
Analytic Code
Not applicable
Data Dictionary
Undecided - It is not yet known if there will be a plan to make this available
Title and more details about the data/document
IPD: Information and research data Ethic form: Complete the ٍEthic form by the patient
When the data will become available and for how long
IPD: 2018 Ethic form: 2018
To whom data/document is available
IPD: Researcher & Patient Ethic form: Patient
Under which criteria data/document could be used
IPD: Ethic form: Awareness of test results
From where data/document is obtainable
IPD: OB & Gyn ward Hormozgan university of medical sciences Ethic form: OB & Gyn ward Hormozgan university of medical sciences
What processes are involved for a request to access data/document
IPD: Vice chancellery Ethic form: Vice chancellery
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