Protocol summary

Summary
The purpose of the study: The purpose of the study is assessing the outcome of blind PCNL and its related effective factors, and then, making a comparison with fluoroscopic-guided PCNL. The main inclusion criteria is presence of Stag-horn renal calculus and the main exclusion criteria is presence of Blood coagulation disorders. We will study 100 patients with kidney stones, who are referred to Shohadaye Tajrish Hospital and are candidates for PCNL. In order to carry out this study, patients will be randomly divided into two equal groups. Blind PCNL in one group and fluoroscopic-guided PCNL in another group will be carried out. Blind PCNL through anatomic landmark, namely lumbar notch, will be carried out. An 18-gauge needle will be inserted with an angle of 30 degrees through skin in the notch area below the 12th rib and will be advanced to the depth of 3-4 cm until it arrives at calyx. The background variables and demographic information will be recorded for each patient. At the end of the operation, KUB and sonography are performed to determine the urinary residue. In addition, in blind PCNL, all cases of punctures and the access locations will be determined by fluoroscopy. Moreover, puncture numbers will be calculated at the end of surgery and surgery complications like hematoma will be determined by sonography.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT138803121267N9
Registration date: 2009-08-17, 1388/05/26
Registration timing: registered_while_recruiting

Last update:
Update count: 0
Registration date
2009-08-17, 1388/05/26
Registrant information
Name
Mojgan Borgheie
Name of organization / entity
Urology and Nephrology Research Center (UNRC), Shahid Beheshti University of Mediacal Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 2256 7222
Email address
research@unrc.ir
Recruitment status
Recruitment complete
Funding source
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University,
Expected recruitment start date
2007-02-20, 1385/12/01
Expected recruitment end date
2011-02-20, 1389/12/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
An assessment of blind PCNL outcomes and the related effective factors and a comparison of the outcomes with the fluoroscopic-guided PCNL
Public title
An assessment of blind PCNL outcomes and the related effective factors and a comparison of the outcomes with the fluoroscopic-guided PCNL
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: Presence of stag-horn renal calculus, caliceal stone with hydronephrosis, or impacted superior ureteral stone, written informed consent Exclusion criteria: More than 5 punctures, Presence of scar, previous operation, Skin infection at the surgical site, presence of blood coagulation disorders
Age
No age limit
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 100
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Street address
UNRC, No.101,9th Boostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Postal code
1666677951
Approval date
2007-01-28, 1385/11/08
Ethics committee reference number
75

Health conditions studied

1

Description of health condition studied
kidney stone
ICD-10 code
N20.0
ICD-10 code description
Calculus of kidney

Primary outcomes

1

Description
Number of punctures during PCNL
Timepoint
At the end of surgery
Method of measurement
observation

Secondary outcomes

1

Description
surgery complications such as hematoma
Timepoint
After surgery
Method of measurement
Sonography

Intervention groups

1

Description
Blind PCNL
Category
Treatment - Surgery

2

Description
PCNL with the guide of floroscopy
Category
Treatment - Surgery

Recruitment centers

1

Recruitment center
Name of recruitment center
Labafi Nejad Hospital
Full name of responsible person
Street address
Labafi Nejad Hospital., 9th Boostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Full name of responsible person
Shabnam Golshan
Street address
UNRC, No.101, Boostan 9th St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Full name of responsible person
Mojtaba Mohammadhosseini Ebne Chenari
Position
Resident
Other areas of specialty/work
Street address
UNRC, No.101, 9th Boostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Postal code
1666677951
Phone
+98 21 2256 7222
Fax
+98 212277954
Email
Research @unrc.ir
Web page address
www.unrc.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Full name of responsible person
Hossein Karami
Position
Professor
Other areas of specialty/work
Street address
UNRC, No.101, 9thBoostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Postal code
1666677951
Phone
+98 21 2256 7222
Fax
+98 212277954
Email
Research @unrc.ir
Web page address
www.unrc.ir

Person responsible for updating data

Contact
Name of organization / entity
Urology and Nephrology Research Center ( UNRC), Shahid Beheshti University, M.C.( SBMU), Tehran, I.
Full name of responsible person
Mozhgan Borgheie
Position
MD
Other areas of specialty/work
Street address
UNRC, No.101, 9th Boostan St., Pasdaran Ave., Tehran, I.R. Iran
City
Tehran
Postal code
1666677951
Phone
+98 21 2256 7222
Fax
+98 212277954
Email
borgheie@unrc.ir
Web page address
www.unrc.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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