Effect of low level laser therapy with 980 nm diode on post endodontic pain after single-visit treatment of necrotic mandibular molars with periapical lesion; A randomized clinical trial

The aim of this study is to determine the effect of 980 nm low-power laser on postoperative pain after a single-visit endodontic treatment in necrotic mandibular molar teeth with periapical lesion in patients referred college of Dentistry, Islamic Azad University of Tehran in 1399-1400

This will be a randomized triple blind clinical trial.

This triple blind clinical trial with randomized allocation is held in Department of Endodontics, Faculty of dentistry, Islamic Azad University, Tehran. The randomization process is performed by the investigator, and the information about the sample intervention is stored in sealed envelopes. Care provider (endodontist) and investigator (dental student) are aware of the group allocation and process. After treatment in intervention group low level laser therapy and in control group no laser will be applied and the effect on post endodontic pain will be evaluated.

Patients included in this study were those in need for root canal treatment on mandibular molars with pulp necrosis diagnosed with vitality tests and with periapical lesions scoring 2 or 3 in accordance with the periapical index classification introduced by Ørstavik et al, they had no pain with pulpal origin and had pain on percussion with VAS > 56. Patients in good health and systemic condition determined by health history and verbal questioning were included. Exclusion criteria were periodontal probing depth greater than 3 mm, swelling or presence of sinus tract, patients taking analgesia 12 hours prior to intervention, teeth with open apices (immature or inflammatory root resorption) and teeth diagnosed to be non-restorable after the endodontic treatment in primary evaluations.

Intervention Group: 980 nm low level laser control group: no laser (placebo)

post-treatment pain

Samples are placed in a randomized 4-block by the method of Balanced block. The randomization process is performed by an individual other than the investigator, and the information about the sample intervention is stored in sealed envelopes in order to randomize in excel software. The envelopes contain 18 items for the case group and 18 for the control group.

Patient is not aware of the research treatment group allocation and process. Care provider (endodontist) and investigator (dental student) are aware of the research treatment group allocation and process. Outcome assessor, data analyser and data safety and monitoring board are not aware of the research treatment group allocation and process.

A part of the information, such as information on the main outcome, can be shared

The start of the access period will be 6 to 12 months after the results are released

Data will only be available to researchers working in academic institutions

Data will be available for dental research centers, universities and public and private health centers. All clinicians using laser to reduce pain after endodontic treatment are allowed to use the documentation. Dr. Mahta Fazlyab dr.mfazlyab@gmail.com +982122564571 No. 9, Faculty of Dentistry Islamic Azad University, 9th Neyestan Ave, Pasdaran Ave.

Applicants can contact the person responsible for the article to receive the information. Dr.Mahta Fazlyab dr.mfazlyab@yahoo.com Faculty of dentistry of Islamic Azad university +982122564571 No. 9, Faculty of Dentistry Islamic Azad University, 9th Neyestan Ave, Pasdaran Ave.

Demand by email to the person responsible for the article Dr.Mahta Fazlyab dr.mfazlyab@yahoo.com