Protocol summary

Summary
The aim of this study was to determine the effects of resistance training and detraining on muscle mass in Tehranian women. Twenty post-menopausal women aged over 50 years old were enrolled. After matched for weight, they were randomly assigned into control and resistance training group. The experimental designed program consisted of 12 weeks of resistance training and four weeks of detraining. Resistance training program was performed three times a week (non-consecutive session), three sets of 10 repetitions for 10 movements at least for 60 min. The exercise testing equipment used in this investigation was Thera-Band tubing. The resistance exercise program was designed for each participant, based on 80%, 85%, and 100% 10-repetition maximum. Control group received no intervention. Skin fold thickness was determined by caliper at baseline and 12 and 16 weeks after the intervention. Percentage of body fat was estimated from skin fold thickness (triceps and subscuplar) by McArdle method. Fat mass and fat free mass were calculated. Range of motion for trunk flexion and extension was determined.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT201111121058N2
Registration date: 2012-01-01, 1390/10/11
Registration timing: retrospective

Last update:
Update count: 0
Registration date
2012-01-01, 1390/10/11
Registrant information
Name
Arash Ghanbarian
Name of organization / entity
Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 2243 2500
Email address
ghanbarian@endocrine.ac.ir
Recruitment status
Recruitment complete
Funding source
Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
Expected recruitment start date
2010-12-20, 1389/09/29
Expected recruitment end date
2011-03-20, 1389/12/29
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of strength training and short term detraining on muscle mass in post menopausal women
Public title
Strength Training and Prevention of Sarcopenia
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion Criteria: post menopausal woman; age over 50 years old. Exclusion Criteria: taking hormone replacement therapy (HRT); use of medications like β-adrenergic blockers, β-agonists, Ca2+ channel blockers and corticosteroids; having diabetes, Parkinson’s disease and peripheral neuropathy.
Age
From 50 years old to 65 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 20
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Research Institute for Endocrine Sciences
Street address
#24, Parvaneh st., Yemen st, Chamran Exp.
City
Tehran
Postal code
193954763
Approval date
2010-09-23, 1389/07/01
Ethics committee reference number
ec344

Health conditions studied

1

Description of health condition studied
Sarcopenia
ICD-10 code
M62.5
ICD-10 code description
Muscle wasting and atrophy, not elsewhere classified

Primary outcomes

1

Description
Muscle Weakness
Timepoint
َAt baseline, After 12 weeks, After 16 weeks
Method of measurement
Caliper

Secondary outcomes

1

Description
Rang of Motion
Timepoint
At baseline, After 12 weeks, After 16 weeks
Method of measurement
Sit and Reach

Intervention groups

1

Description
The experimental designed program consisted of 12 weeks of resistance training and four weeks of detraining. Resistance training program was performed three times a week (non-consecutive session), three sets of 10 repetitions for 10 movements at least for 60 min. The exercise testing equipment used in this investigation was Thera-Band tubing. The resistance exercise program was designed for each participant, based on 80%, 85%, and 100% 10-repetition maximum.
Category
Prevention

2

Description
Without any Intervention in Control Group
Category
N/A

Recruitment centers

1

Recruitment center
Name of recruitment center
Health Club
Full name of responsible person
Dr. Arash Ghanbarian
Street address
Research Institute for Endocrine Sciences, #24 Parvaneh st., Yemen st, Chamran Exp.
City
Tehran

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Research Institute for Endocrine Sciences
Full name of responsible person
Dr. Fereidoun Azizi
Street address
Research Institute for Endocrine Sciences, #24, Parvaneh st., Yemen st, Chamran Exp.
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Research Institute for Endocrine Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Research Institute for Endocrine Sciences
Full name of responsible person
ِDr. Arash Ganbarian
Position
Senior Investigator, M.D.
Other areas of specialty/work
Street address
#24, Parvaneh st., Yemen st, Chamran Exp.
City
Tehran
Postal code
Phone
+98 21 2243 2500
Fax
Email
ghanbarian@endocrine.ac.ir
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
Full name of responsible person
Dr. Arash Ghanbarian
Position
Senior Investigator, M.D.
Other areas of specialty/work
Street address
#24, Parvaneh st., Yemen st, Chamran Exp.
City
Tehran
Postal code
Phone
+98 21 2243 2500
Fax
Email
ghanbarian@endocrine.ac.ir
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences
Full name of responsible person
Maryam Delshad
Position
M.Sc
Other areas of specialty/work
Street address
City
Postal code
Phone
Fax
Email
delshad.maryam@yahoo.com
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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