The effects of virtual reality intervention with and without transcranial direct current stimulation on motor and cognitive performances in sedentary adolescent girls

The effects of 4 weeks of virtual reality training with and without transcranial direct current stimulation on motor performance (motor coordination, balance) and cognitive (reaction time, working memory, cognitive flexibility) of sedentary adolescent girls.

A single-blind clinical trial with a control group and parallel groups, and randomized in a block method on 36 sedentary adolescent girls. The website www.randomization.com will be used for randomization.

This research will be carried out in Razi University. First, the research variables will be measured, Then, 3 groups participating in the research will receive the desired interventions.After completing the interventions, the research variables will be measured again.In this research, the participants and the main research team will be blinded.

Being right-handed; having physical health; lack of physical activity; having normal vision or corrected vision; having an age range of 15 to 18 years old; no history of head injury, previous seizures; lack of brain implants, heart battery; no drug addiction; not suffering from severe diabetes, asthma; not simultaneously participating in another study

1- Virtual reality group + real transcranial direct current stimulation 2- Virtual reality group + sham direct current stimulation 3- The control group did not participate in virtual reality exercises and did not receive direct brain current stimulation

Change in hand-eye coordination; bimanual coordination; static balance; dynamic balance; simple reaction time; selective reaction time; working memory; cognitive flexibility

In this study, permuted block randomization via the www.randomization.com website will be used. To do so, first, a unique number will be allocated to each subject as the identifier code and, a 36-digit sequence (equal to sample size) will be created. Then, treatment labels including: 1 (virtual reality group + real trans cranial direct current stimulation, 2 (virtual reality group + sham trans cranial direct current stimulation); 3 (The control group: will be defined in the relevant section on the website). After defining the treatment groups and to avoid potential problems associated with equal block sizes, permuted block randomization with different block sizes will be applied. In this case, by knowing the sample size, the block sizes will be unequal and a multiple of the number of treatment groups (for example, block sizes of 2, 4, 6, or 8). The website has the ability to randomly specify the sequence of blocks with different sizes. In the final step and upon performing the 'Generate Plan' on the website, all subjects will be randomly assigned to blocks of different sizes that already have a random sequence. Finally, by using the number (code) assigned to each subject and checking the blocks, the group of each subject will be determined.

The present study is a single-blind study, in which participants are blinded about receiving real or sham stimulation while, based on the nature of virtual reality, there will be no blinding for virtual reality interventions. In order to blind the two groups receiving brain stimulation, they do not know the settings of the device whether it is real or sham. Both groups will receive stimulation (sham or real) for 20 minutes.

All data are shared after the de-identification of the participants

3 months after publication

All individuals upon formal request

Data sharing requests are accepted for any purposes

To obtain any data/document, please send an e-mail to nasrin shahbazi , a PhD student at Razi University, through the following e-mail address: n_shahbazi_69@yahoo.com

Upon formal request, mentioning due reasons, and providing full personality details, data will be sent after 72 h via e-mail.