Title : Clinical evaluation of the effect of the combination of herbal cream containing Rosmarinus officinalis, , Malva sylvestris, Foeniculum vulgare extract and Oenothera biennis and Bitter Almond Oil for treatment of hair loos on patients with Areata Alopecia

The purpose of using these plants is : combating for hair loss, increasing its regrowth by increasing blood circulation, providing nutrients for the activity of hair follicles and coming out of the resting stage.

This research is a clinical double blind trail that 150 patients with the diagnosis of Alopecia areata referred to the Skin and Hair Clinic

Physician examination and survey by questionnaire

Inclusion: Suffering from total hair loss, alopecia in the head area, size of the lesion below 10 square centimeters, completing the consent form and agreeing to participate in the study, patients aged 18 to 60 years Exclusion: Patient unsatisfaction, pregnancy during the study, a lactating woman, universal alopecia areata, ophiiasis alopecia areata, sensitivity to triamcinolone, minoxidil or herbal combination before treatment, receiving oral or topical و Special patients, patients with migraine and epilepsy

Men treated with minoxidil and herbal cream prepared daily and checked up by a doctor monthly - Women with alopecia areata (AA) who are treated with minoxidil and herbal cream prepared daily and checked-up by a doctor monthly Description Patients in case group received Glycyrrhiza glabra tablets, 2 tablets three times per day

The full growth in the empty file.

Samples were 150 patients and were selected by simple random sampling and Random assignment or random placement that is an experimental technique for assigning human participants or animal subjects to different groups in an experiment (e.g., a treatment group versus a control group) using randomization, such as by a chance procedure (e.g., flipping a coin). This ensures that each participant or subject has an equal chance of being placed in any group. Moreover, grouping of samples has been done using Randomizer(RA) software. Patients were divided into 6 groups of 25. For each treated group, a control group (triamcinolone cream) was placed separately, and the entrance of patients into these groups is random. Grouping of samples has been done using RA software. The blinding of this research is on behalf of the patient and the drug distributor. The homogenization of the studied groups is based on the variables: sex, age, type of alopecia areata and severity of hair loss in the head area. In general, randomization of patients was done based on coding.

The single blindness of the study was performed in this process that at first the mentioned drugs received code without any labels and the patient selected one of the two drugs randomly. Then, the name of each person and the drug code provided to him registered by the secretary. Neither the patient nor the doctor was not aware of the type of medication. The name of each person and his drug was specified only during analyzing the data, and completed the patients' information profile by mentioning the name of the drug received by them.

The project needs to complete.